The Relationship between the Changes of Blood NT-proBNP Levels and Postoperative Atrial Fibrillation Occurance in Coronary Artery By-Pass Grafting Surgery Patients
Background: The new onset of atrial fibrillation (NOAF) can be occurred
after coronary artery bypass grafting (CABG) surgery. NOAF can be occurred
because of postoperative severe hemodynamic instability, long duration of ICU
and hospital staying time, morbidity and mortality. Our aim of this study was
to investigate whether N-terminal pro-brain natriuretic peptide (NT-proBNP) is
a cause of NOAF after CABG. Methods: Forty CABG patients were enrolled for this
study. Twenty patients operated on cardiopulmonary bypass (Group I; n: 20). The
remaining patients have operated using a beating heart technique (Group II; n:
20). The NT-proBNP levels were calculated pre- and postoperatively. Results:
High rate of NOAF was detected in group I patients (P < 0.05). In both
groups, the NT-proBNP levels were low with sinus rhythm. The NT-proBNP blood
levels in different times (T1, T2, T3, T4) among Group I were found higher than
Group II. Conclusions: Our research demonstrated that there was a strongly
close relationship between blood NT-proBNP levels’ and atrial fibrillation
occurrence in CABG patients. According to our results to detect postoperative
AF development in early time and its treatment, blood NT-proBNP levels can be
calculated in those patients for reducing morbidity and mortality due to AF.
Cite this paper
Azboy, D. , Simsek, E. , Erdolu, B. , Temizturk, Z. , Yilmaz, M. A. and Karapinar, K. (2016). The Relationship between the Changes of Blood NT-proBNP Levels and Postoperative Atrial Fibrillation Occurance in Coronary Artery By-Pass Grafting Surgery Patients. Open Access Library Journal, 3, e1818. doi: http://dx.doi.org/10.4236/oalib.1101818.
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