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Nov 28, 2022Open    Access

In-Silico and Biological Analysis of B-Cell Lymphoma-2 Gene and Genetic Mutation as Diagnostic Marker in Childhood Sudanese Acute Lymphoblastic Leukemia Patients, Gezira State, Sudan (2018)

Samar Abdalaziz, Asad Adam Abbas, Soad Fadal Allah, Yousif Abdelhammed, Ozaz Y. M. Ahmed, Hisham N. Altayb
Objective: To analyze the BCL2 genetic as diagnostic marker among acute lymphoblastic leukemia in childhood Sudanese patients, to detect genetic polymorphism in BCL2 in childhood acute lymphoblastic leukemia patients using Polymerase chain reaction (PCR) and DNA sequencing technique to confirm the harmfulness of the detected mutation using in silico analysis. Material and Methods: Venous blood was drained by means of clean venipuncture into a labeled 5 ml K-EDTA tubes. Subsequent mixing of blood...
Open Access Library J.   Vol.9, 2022
Doi:10.4236/oalib.1109400


Jul 20, 2021Open    Access

Working Family Caregivers’ Perception of Usefulness of an Online Employee Assistance Support Tool: A Pilot Study

Debra Gibbs, Julia Bilotta, Chanté Bowens, Monica Dougherty, Emma Murphy, Nicki Richardson, Molly Schneider-Adams
Objectives: The population of older adults is growing rapidly, creating high demand for the involvement of working family caregivers. This concurrent mixed-methods study sought to obtain information from working family caregivers regarding their perceptions of the usefulness of an online employee assistance support tool. Methods: Working family caregivers (n = 15) participated in a semi-structured focus group completing a demographic survey and the Modified Caregiver Strain Index (MCSI). Results...
Open Access Library J.   Vol.8, 2021
Doi:10.4236/oalib.1107663


May 31, 2021Open    Access

Nursing Care in the Functional Disabilities of the Elderly in Primary Health Care: Systematic Review with Meta-Synthesis

Ana Gracinda Ignacio Da Silva, Maria Bárbara Freire Lameira, José Eduardo Resende Campos, Luciana Maria Andrade Neri, Juliana Conceicao Dias Garcez, Gabriel Fazzi Costa, Maria Rute de Souza Araujo, Milena Farah Damous Castanho Ferreira, Daniele Melo Sardinha
When considering the elderly, we must realize the profound particularities in their daily lives, because the elderly has vulnerabilities that result from the aging process. This study aims to develop a systematic review followed by meta-synthesis based on the findings of qualitative primary scientific research, on nursing care in the face of Functional Incapacity of the Elderly in Primary Health Care starting with the research question: How does the nursing care process for elderly people with f...
Open Access Library J.   Vol.8, 2021
Doi:10.4236/oalib.1107431


May 28, 2021Open    Access

A Journal Article Critique of “Motivational Interviewing and Exercise Program for Community-Dwelling Older Persons with Chronic Pain”

Hamzah M. Alghzawi, Fatima K. Ghanem
This article provides a critical review of a published article entitled “Motivational Interviewing and Exercise Program for Community-Dwelling Older Persons with Chronic Pain”. The reviewed article aimed to examine the effectiveness of an integrated motivational interviewing and physical exercise program (MIE) on pain, physical and psychological functions, quality of life, self-efficacy, and compliance with exercise. A randomized pretest-posttest with a control group experimental design was used...
Open Access Library J.   Vol.8, 2021
Doi:10.4236/oalib.1107456


Dec 31, 2020Open    Access

Study on the Incidence of Stroke-Related Sarcopenia in Hospitalized Male Patients

Guang Liu, Chongwen Zheng, Donghao Zhou
Objective To observe and analyze the incidence of sarcopenia in male patients with stroke-related sarcopenia. Methods From June 2018 to June 2019, the muscle mass of 45 patients who had recovered from stroke, who underwent DXA testing at Linyi People’s Hospital during the period from June 2018 to June 2019. During the same period, 50 healthy subjects served as the control group to explore the muscles of stroke patients. Results The incidence of stroke-related sarcopenia was higher. The SMI, grip...
Open Access Library J.   Vol.7, 2020
Doi:10.4236/oalib.1107009


Dec 31, 2020Open    Access

Experience of Treating 69 Cases of Gastroc Ardical Syndrome with Traditional Chinese Medicine

Yanzhi Wang, Binglin Liu, Zhenchao Liu, Guang Liu, Donghao Zhou
Aims: To explore the clinical efficacy of TCM in the treatment of gastroc ardical syndrome, and to summarize the experience of TCM treatment of gastroc ardical syndrome. Method: A retrospective summary of 69 patients with gastroc ardical syndrome treated by Binglin Liu, an old expert in Linyi Hospital of Traditional Chinese Medicine, according to the patient’s clinical symptoms and prescriptions, summarizes the TCM classification and treatment methods of this disease. Results: The TCM syndromes ...
Open Access Library J.   Vol.7, 2020
Doi:10.4236/oalib.1107001


Apr 30, 2020Open    Access

Dual Contraception Use and Associated Factors among HIV Positive Women Follow-Up at Treatment Center Unit of Yaounde Central Hospital, Cameroon

Marcellin Tsafack, Felix Essiben, Romaric Joel Momo, Goerge Kamsu Moyo, Yannick Massaga Mpoah, Robinson Enow Mbu
Background: A less risky sexual behaviour for sexual and reproductive health among HIV positive women is essential for their well-being and that of their sexual partners and children. The aim of this study was to assess the frequency of dual contraception method use and factors associated among HIV positive women follow-up at the treatment center unit (TCU) at Yaounde Central Hospital (YCH). Methods: It was a transversal study done for 6 months at YCH. A sample of 294 HIV positive women among 32...
Open Access Library J.   Vol.7, 2020
Doi:10.4236/oalib.1106225


Sep 03, 2019Open    Access

Overview of Post-Stroke Epilepsy

Wadi Bnouhanna, Amal Satté, Jamal Mounach, Hamid Ouhabi
Stroke is the most common cause of seizures, symptomatic epilepsy, and status epilepticus in elderly. Symptomatic stroke-related seizures symptoms are dependent on lesions topography. All types of focal seizures can be observed. Many clinical studies make a distinction between early (within 7 to 14 days of stroke onset) and late (beyond 14 days of stroke o
...
Open Access Library J.   Vol.6, 2019
Doi:10.4236/oalib.1105705


May 18, 2018Open    Access

Relevant Factors for Sarcopenia in Hyperthyroidism Patients

Zhenchao Liu, Feifei Xia, Xinbo Zhao, Donghao Zhou
In recent years, sarcopenia began to receive attention. Not only the elderly, hyperthyroidism patients also suffer from sarcopenia. The purpose of this study is to explore the relevant factors for sarcopenia in hyperthyroidism patients. [Methods]: Dual energy X-ray was used to detect the muscle mass in 101 hyperthyroidism patients (23 males and 78 females, mean age 45.77 ± 15.02 years), and calculate SMI. Pearson correlation analy
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Open Access Library J.   Vol.5, 2018
Doi:10.4236/oalib.1104620


Mar 26, 2018Open    Access

The Peripheral Hypotheses of Hypothalamic Aging

Zi-Jian Cai
It is well known that the hypothalamic changes in control of hormones determine the chronological sequence of aging in mammals. For decades, it has been demonstrated in humans that the hypothalamic nuclei manifest heterogeneity in degeneration during aging, with the neuron number decreasing in both the suprachiasmatic nucleus (SCN) and the preoptic sexually dimorphic nucleus (SDN-POA) in the process of senescence, while the neuron
...
Open Access Library J.   Vol.5, 2018
Doi:10.4236/oalib.1104445


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