Evaluation of Effect of Rutin in Diabetes Rat Gastropathy

The antioxidant effect of Rutin was investigated in diabetic rats. The Alloxan monohydrate was used to induce the diabetes innormal rats. The animals were divided into two groups.The Istgroup comprising control group treated with vehicle while in IIndgroup Diabetes was induced. The Gastric emptying was evaluated by Phenol red assay method and Intestinal transit by Charcoal meal Method. The results indicated that 20 mg/kg and 40 mg/kg of Rutin improved gastric emptying and intestinal transit significantly and in dose dependent manner. The result was analyzed statistically. The present study revealed the usefulness and beneficial value of rutin in the treatment of disorder of gastric emptying and intestinal transit in diabetes gastropathy