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含能材料  2010 

高效液相色谱法分离TAT和TRAT

DOI: 10.3969/j.issn.1006-9941.2010.02.023

Keywords: 分析化学,1,3,5,7-四乙酰基-1,3,5,7-四氮杂环辛烷(TAT),1,3,5-三乙酰基-1,3,5-三氮六氢均三嗪(TRAT),奥克托今(HMX),黑索今(RDX),高效液相色谱(HPLC)

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Abstract:

建立了高效液相色谱分离高能炸药奥克托今(HMX)合成反应前体1,3,5,7-四乙酰基-1,3,5,7-四氮杂环辛烷(TAT)和1,3,5-三乙酰基-1,3,5-三氮六氢均三嗪(TRAT)的分析方法,并利用高效液相-质谱联用技术(HPLC-MS)对TAT和TRAT的色谱峰进行了结构确认。优选后的色谱分离条件为硅胶柱(4.6mm×250mm,5μm),流动相:乙腈:水=75:25(V/V),流速为1.0mL·min-1,检测波长:215nm,进样量为20μL。在上述条件下,TAT和TRAT分别在10~1000μg/ml和30~1000μg/ml范围内与响应信号呈良好的线性关系(R2=0.9999,R2=0.9996),Rs=1.5。

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