Total of 360 articles.


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Nov 05, 2024Open    AccessArticle

Support for the Hypothetic Remote Memory Formation via Heterosynaptic LTD-mediated Synaptic Degeneration

Zi-Jian Cai
Recently, from the cellular forms of memory in the brain concurrently as both homosynaptic long-term potentiation (LTP) and heterosynaptic long-term depression (LTD), it was hypothesized by Cai a new mechanism for the formation of stable remote memory in the brain as heterosynaptic LTD-mediated irreversible neuronal degeneration. This chapter aims to further support such a hypothesis. It has recently been shown that LTD, including heterosynaptic LTD, proceeded with the intracellular clearance of...

Neuroscience  Neurology  Geriatrics  Cell Biology  Biochemistry  Physiology 

Nov 05, 2024Open    AccessArticle

The Hypothetic Nutrient Constraint to Continuously Maintain as Gradient from Gastrula to Postnatal Development: An Important Mechanism for Recapitulation

Zi-Jian Cai
It was suggested by Cai a theory that the nutrient gradient differentiate the cellular living states to form the three germ layers of animal embryonic gastrula differential developing to three different subsequent fates, with the endoderm manifesting cellular living states in nutritious condition and forming the epithelium of digestive and respiratory system; the ectoderm manifesting cellular living states of nutrient dependence and environmental effects, and giving rise to the nervous and epith...

Cell Biology  Gynecology & Obstetrics  Biochemistry  Developmental Biology  Evolutionary Studies 

Aug 21, 2024Open    AccessArticle

Neuropsychoanalytic Prerequisite for Diagnosis of Psychiatric Unbalance

Zi-Jian Cai
It was recently added by Cai to neuropsychoanalysis the ascending noradrenergic (NA), serotonergic (5-HT) and acetylcholinergic (ACh) systems, differentiating the emotions/memories/conscious balance in waking and sleep for depression, as well as the ascending dopaminergic (DA) and ACh systems to motivation/selfishness/knowledge balance for schizophrenia. For psychiatric diagnosis, it is just delineated the psychological unbalance resulting from the detected pathologies by neuropsychoanalytic int...

Neuroscience  Psychiatry & Psychology 

Aug 21, 2024Open    AccessArticle

Amnesic Pathologies in Regulation of Dopamine as Supplement to Wernicke-Korsakoff Syndrome: A Limbic-Reticular Coupling View

Zi-Jian Cai
Background: It was suggested by the limbic-reticular coupling theory that the hippocampus and amygdala regulate such descending limbic structures as the mammillary bodies, septum, hypothalamus and habenula, and in turn regulate the ascending noradrenergic, serotonergic, dopaminergic and cholinergic systems to consolidate and recall declarative memory, while the anterior and mediodorsal thalamic nuclei of Wernicke-Korsakoff syndrome beyond limbic-reticular coupling be related else to familiarity....

Neuroscience  Neurology  Anatomy & Physiology  Cognitive Disorders  Pathology 

May 19, 2023Open    AccessArticle

What it Takes to Inspire: A comparative Role Model Analysis of Students in Entrepreneurship and Teaching

Anh Dinh,Diana Püplichhuysen
According to career education and learning research, role models can significantly influence others’ decision-making processes and career choices. Such effects may be particularly relevant for potential entrepreneurs and future teachers, as much learning in these professions relies heavily on role models. Thus, educating students who desire to work in these fields might profit from a more role model-centered approach. However, research has shown that university educators rarely serve as role mod...

Entrepreneurship 
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May 19, 2023Open    AccessArticle

EL COMERCIO SOCIAL EN TIEMPOS DE CRISIS: EL CASO DE CONSUMELOCAL.ME

Marcos Pérez Mendoza
The trade or exchange of products has changed from the face-to-face format to a virtual one. Commerce then starts from a traditional environment to a virtual environment in the face of the growing impact of the internet, giving space to electronic commerce. Derived from the COVID-19 pandemic, face-to-face purchases were limited due to confinement, special days and hours, thereby causing an economic crisis throughout the globe. The MSMEs in search of virtual means to advertise th...

Supply Chain Management  Strategic Management Policy  Business Theories  Behavioral Economics  Sociology  Project Management and Strategy  Project Management  Economics  Tourism Economy  Business Management  Culture  Public Administration  Business Ethics and Corporate Social Responsibility  Management Organization  Socioeconomics  Educational Economy and Management  Business Communication  Business Analysis  Corporate Governance  Accounting 

May 19, 2023Open    AccessArticle

Effect of non-thermal atmospheric pressure plasma on MDA-MB-231 breast cancer cells

Ramin Mehrabifard, Hassan Mehdian, Mahdi Bakhshzadmahmoudi
Cold atmospheric plasma (CAP) has received great attention due to its noteworthy ability, and has also been widely studied over few decades in physics, biology and medicine. The purpose of this study is to evaluate the cold atmospheric pressure plasma effects on the proliferation of breast cancer cells. MDAMB-231 was used for this experiment. MDA-MB-231 cells were cultured in 24-well plate and treated with non-thermal plasma. The viability of the cancer cells was determined by MTT assay. Differe...

Plasma  Cell Biology 

May 19, 2023Open    AccessArticle

Video Capsule Endoscopy and Ingestible Electronics: Emerging Trends in Sensors, Circuits, Materials, Telemetry, Optics, and Rapid Reading Software

Dylan Miley, Leonardo Bertoncello Machado, Calvin Condo, Albert E. Jergens, Kyoung-Jin Yoon, Santosh Pandey
Real-time monitoring of the gastrointestinal tract in a safe and comfortable manner is valuable for the diagnosis and therapy of many diseases. Within this realm, our review captures the trends in ingestible capsule systems with a focus on hardware and software technologies used for capsule endoscopy and remote patient monitoring. We introduce the structure and functions of the gastrointestinal tract, and the FDA guidelines for ingestible wireless telemetric medical devices. We survey the advanc...

Electric Engineering  Drugs & Devices  Genetic Engineering  Biological Engineering  Evidence Based Medicine  Chemical Engineering & Technology  Gastroenterology & Hepatology  Diagnostics 

May 19, 2023Open    AccessArticle

Unidirectional, electrotactic-response valve for Caenorhabditis elegans in microfluidic devices

Santosh Pandey
We report a nematode electrotactic-response valve (NERV) to control the locomotion of Caenorhabditis elegans (C. elegans) in microfluidic devices. This nonmechanical, unidirectional valve is based on creating a confined region of lateral electric field that is switchable and reversible. We observed that C. elegans do not prefer to pass through this region if the field lines are incident to its forward movement. Upon reaching the boundary of the NERV, the incident worms partially penetrate the fi...

Animal Behavior  Zoology  Mathematical Biology  Veterinary Medicine  Cell Biology  Parasitology  Developmental Biology  Evolutionary Studies  Bioengineering  Bioinformatics  Environmental Sciences  Biophysics 

May 19, 2023Open    AccessArticle

Characterization of a MEMS BioChip for planar patch-clamp recording

Santosh Pandey, Mehrotra, R. Wykosky, S. White, M.H.
We describe a planar MEMS silicon structure to record ion channel currents in biological cells. The conventional method of performing an electrophysiological experiment, 'patch-clamping', employs a glass micropipette. The micropipette tip is a source of thermal noise because of its inherent, tapered, conical structure, giving rise to a large pipette resistance. This pipette resistance, when coupled with the biological cell capacitance, limits the available bandwidth of single ion channel recordi...

Taxonomy  Microbiology  Biochemistry  Biodiversity  Developmental Biology  Bioengineering  Bioinformatics  Environmental Sciences  Agricultural Science  Computational Biology  Genetics  Cell Biology  Food Science & Technology  Parasitology  Synthetic Biology 

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