The present work describes the validation of an analytical method for
chromatographic determination of chlorimuron ethyl herbicide (compound of
sulphonylurea group) in sediments, in according with Brazilian legislation,
following the guidance and normative documents of INMETRO (DOQ-CGCRE-008) and
ANVISA (Resolution RE no. 899-2003). The results show that the chromatographic
method demonstrated to be selective, accurate, precision and linear over the
concentration range of 5.0 - 1000.0 μg·L﹣1. Besides, limits of quantitation and determination were
satisfactory, 29.48 and 8.84 μg·L﹣1, both determined by calibration curve. The method proposed
also showed good results for assays of recovery, with confidence intervals
between 80 and 100%, approximately, with accuracy and precision.
Cite this paper
Nunes, R. R. , Santos, B. H. F. and Rezende, M. O. D. O. (2016). Analytical Procedures and Method Validation for Determination of Chlorimuron Ethyl in Sediments. Open Access Library Journal, 3, e2398. doi: http://dx.doi.org/10.4236/oalib.1102398.
ANVISA—Agência
Nacional de Vigilancia Sanitária (1987) Monografias técnicas do ministério da
saúde sobre substancias com acao tóxica sobre animais ou plantas, Portaria 9
10/85. ANVISA,
Brasília.
Zanella, R., Primel, E.G., Gon?alves, F.F., Kurz, M.H.S. and Mistura, C.M. (2003) Development and Validation of a High-Performance
Liquid Chromatographic Procedure for the Determination of Herbicide Residues in
Surface and Agriculture Waters. Journal of Separation Science, 26, 935-938. http://dx.doi.org/10.1002/jssc.200301309
INMETRO—Instituto
Nacional de Metrologia, Normalizacao e Qualidade Industrial (2011) Orientacoes sobre Validacao de Métodos de
Ensaios Químicos,
DOQ-CGCRE-008. INMETRO: Brasília.
ANVISA—Agência
Nacional de Vigilancia Sanitária (2003) Guia para validacao de métodos
analíticos e bioanalíticos, Resolucao RE no 899. ANVISA, Brasília.
ISO—International Standard
Organization (1999) General
Requirements for the Competence of Testing and Calibration Laboratories,
ISO/IEC 17025. ISO, Genebra.
ANA—Agencial
Nacional de águas, CETESB—Companhia
Ambiental do Estado de Sao Paulo (2011) Guia Nacional
de Coleta e Preservacao de Amostras: água, Sedimentos, Comunidades Aquáticas e
Efluentes Líquidos. ANA, Brasília.