Method:
the study was conducted to analyze the correlation between Fitz Hugh-Curtis
syndrome (FHCS) with the occurrence of hydrosalpinx, and the risk for
hydrosalpinx occurrence due to FHCS. This
observational retrospective study was conducted by reviewing the medical
records of 315 infertile women who underwent
gynecologic laparoscopy procedure from 2011 to 2016. FHCS was
characterized by the presence of perihepatic adhesion between Glisson’s capsule
and anterior peritoneum, forming “violin string” appearance, and categorized as a mild,
moderate, and severe form. The comparison of the degree of FHCS and
hydrosalpinx occurrence was analyzed using χ2 test. The odds ratio was calculated to analyze the risk for hydrosalpinx
occurrence in the presence of FHCS. The p-value < 0.05
was considered significant. Of 315 subjects, FHCS was found in 108 subjects
(34.3%), while hydrosalpinxwas found in 107 subjects (34%). Sixty-eight
subjects (63%) have a severe degree of FHCS. In subjects with FHCS, 64.5% had
hydrosalpinx. There was a significant difference in the perihepatic adhesion
degree and the occurrence of hydrosalpinx (χ2 = 7.55; p = 0.02).
There was a significant difference in hydrosalpinx
occurrence between FHCS-positive and-negative group (χ2 = 65.60, p < 0.05). The risk of hydrosalpinx occurrence was higher in the presence of FHCS compared with those without FHCS (OR 7.87; 95%
CI 4.64-13.33, p < 0.05). Conclusion:
the risk for hydrosalpinx was elevated in FHCS.
Cite this paper
Bayuaji, H. , Permadi, W. and Nataprawira, H. M. N. (2017). The Fitz Hugh-Curtis Syndrome and Hydrosalpinx: Analysis of Findings in Gynecologic Laparoscopy Procedure of Infertile Women. Open Access Library Journal, 4, e3742. doi: http://dx.doi.org/10.4236/oalib.1103742.
Practice Committee of the American Society
for Reproductive Medicine
(2015) Role of Tubal Surgery in the Era of Assisted Reproductive Technology: A
Committee Opinion. Fertility and
Sterility, 103,
e37-e43. https://doi.org/10.1016/j.fertnstert.2015.03.032
Practice
Committee of American Society for Reproductive Medicine in Collaboration with Society
of Reproductive Surgeons (2008)
Salpingectomy for Hydrosalpinx Prior to in
Vitro Fertilization. Fertility and Sterility, 90, S66-S68.
Keane,
J.A., McKimm, R.J. and David, C.M. (1982) Perihepatitis Associated with Pelvic
Infection: The Fitz-Hugh-Curtis Syndrome. The
New Zealand Medical Journal, 95,
725-728.
Cusimano,
A., Abdelghany, A.M. and Donadini, A. (2016) Chronic Intermittent Abdominal Pain
in Young Woman with Intestinal Malrotation, Fitz-Hugh-Curtis Syndrome and Appendiceal
Neuroendocrine Tumor: A Rare Case Report and Literature Review. BMC Women’s Health, 16, 3. https://doi.org/10.1186/s12905-015-0274-2
Sharma, J.B.,
Malhotra, M. and Arora, R. (2002) Incidential Fitz-Hugh-Curtis Syndrome at Laparoscopy
for Benign Gynecologic Conditions. International
Journal of Gynecology & Obstetrics, 79,
237-240. https://doi.org/10.1016/S0020-7292(02)00231-X
Kobayashi, Y.,
Takeuchi, H., Kitade, M., Kikuchi, I., Sato, Y. and Kinoshita, K. (2006)
Pathological Study of Fitz-Hugh-Curtis Syndrome Evaluated from Fallopian Tube
Damage. Journal of Obstetrics and
Gynaecology Research, 32, 280-285. https://doi.org/10.1111/j.1447-0756.2006.00399.x
Gomel,
V. and Taylor, E. (2008) Reconstructive Tubal Surgery. In: Rock, J.A. and Jones, H.W., Eds., Te Linde’s Operative Gynecology,
Lippincott Wiliams & Wilkins, Philadelphia, 403-437.
Johnson, N., van Voorst, S., Sowter, M.C., Strandell, A. and
Mol, B.W. (2010) Surgical Treatment for Tubal Disease in Women Due to Undergo in Vitro Fertilisation. The Cochrane Database of Systematic Reviews, No. 1, CD002125.
Strandell,
A. (2000) The Influence of Hydrosalpinx on IVF and Embryo Transfer: A Review. Human Reproduction Update, 6,
387-395. https://doi.org/10.1093/humupd/6.4.387
D’Arpe, S.,
Franceschetti, S., Caccetta, J., Pietrangeli, D., Muzii, L. and Panici, P.B.
(2015) Management of Hydrosalpinx before IVF: A Literature Review. Journal of Obstetrics and Gynaecology, 35,
547-550. https://doi.org/10.3109/01443615.2014.985768
Ozmen,
B., Diedrich, K. and Al-Hasani, S. (2007) Hydrosalpinx and IVF: Assessment of
Treatments Implemented Prior to IVF. Reproductive
BioMedicine Online, 14, 235-241.
Peter, N.G., Clark,
L.R. and Jaeger, J.R. (2004) Fitz-Hugh-Curtis Syndrome: A Diagnosis to Consider
in Women with Right Upper Quadrant Pain. Cleveland
Clinic Journal of Medicine, 71, 233-239. https://doi.org/10.3949/ccjm.71.3.233
Perquin, D.A., Beersma, M.F., de Craen, A.J. and Helmerhorst,
F.M. (2007) The Value of Chlamydia Trachomatis-Specific IgG Antibody Testing
and Hysterosalpingography for Predicting Tubal Pathology and Occurrence of
Pregnancy. Fertility and Sterility, 88, 224-226.
Onoh, R.C., Mgbafuru, C.C., Onubuogu, S.E. and Ugwuoke, I.
(2016) Fitz-Hugh- Curtis
Syndrome: An Incidental Diagnostic Finding in an Infertility Workup. Nigerian Journal of Clinical Practice, 19,
834-836. https://doi.org/10.4103/1119-3077.181357
Audebert,
A., Pouly, J.L., Bonifacie, B. and Yazbeck, C. (2014) Laparoscopic Surgery for
Distal Tubal Occlusions: Lessons Learned from a Historical Series of 434 Cases. Fertility and Sterility, 102, 1203-1208.
Sharma, J.B., Roy, K.K., Gupta, N., Jain, S.K., Malhotra, N.
and Mittal, S. (2007) High Prevalence of Fitz-Hugh-Curtis Syndrome in Genital
Tuberculosis. International Journal of
Gynecology & Obstetrics, 99,
62-63.
