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匹配条件： “Mustapic” ，找到相关结果约7条。
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THE ROLE OF HUMAN RESOURCE IN THE SUCCESS OF SMALL HOTELS
Mustapic, Dragan
- , 2017, DOI: 10.2507/IJVA.3.2.6.39

Abstract: Sa？etak This paper is an attempt to explore and prove that human resources in small hotels are a fundamental factor in the success of their business. Ten volatile human resources variables included: satisfaction of job-seekers; career development; motivation; a tendency to continuous learning; commitment to the organization; innovation and creativity; identification with the organization; relationship to work; relationship to quality of service; the likelihood of accepting changes in business. Three research goals have been set: 1. Prove that human resources are the underlying and primary resources and capital that directly affect the operation of small hotels. 2. Prove that human resource performance and resource management is fundamentally different from performance and management in large hotels. 3. Prove that human resources are essential elements in achieving growth, competitive positions, and market share of small hotels. The research was based on a quota, stratified sample. The sample size would be 200 examinees (n = 200). The sample was selected from small hotels in the four counties of Dalmatia. Dubrovnik-Neretva, Split-Dalmatia, ？ibenik-Knin and Zadar. Out of these counties, the total quota of fifty (50) small private hotels was selected. It is proven that human resources are the underlying and primary resources that directly affect the business of small hotels. Of all ten determinants of business success, several determinants have been shown to have a high correlation with human resource variables

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Instability without collapse. Presidential resignations: Argentina in 2001
Mustapic,Ana Maria;
Desarrollo Económico (Buenos Aires) , 2006,

Abstract: since the 1980s, there have been numerous presidential resignations in different countries in latin america. with respect to this phenomenon, this article puts forward two questions: what circumstances are most favorable for provoking presidents to resign and what is the impact on the presidential system. to address these questions, a case study is used, that of the presidency of de la rúa in argentina (1999-2001) with the aim of constructing a hypothesis that should be tested by additional research. this analysis contends that argentine presidential resignations took two forms in accordance with the distribution of party power in congress: a) a parliamentary response to the crisis and b) a presidential response to the crisis. the first occurred in a multiparty context that facilitated the formation of alternative parliamentary majorities. within this framework, congress deprived the president of support, precipitating his departure. the second seems to be characteristic of contexts that are bipartisan or in which there is a predominant party. in this case, it is the departing president who, within a crisis situation, manages to oversee an orderly succession. as for the impact of presidential resignations on the functioning of presidential regimes, the article puts forward the importance of redefining the place of the fixed term as a characteristic of presidentialism. in light of the numerous presidential resignations, the fixed presidential mandate does not seem to be a necessary component of the definition of presidentialism as it is, in contrast, for legislators. from this another question arises: when analyzing the political dynamic of presidentialism, it is necessary to incorporate presidential resignation as a possible factor.

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Argentina: la crisis de representación y los partidos políticos
Ana María MUSTAPIC
América Latina Hoy , 2009,

Abstract: RESUMEN: El artículo analiza la crisis de representación de los partidos argentinos a partir de dos dimensiones: la relación partido-electorado y la relación partido-gobierno. Con la primera se procura dar cuenta de las restricciones que coloca el sistema electoral federal a la consolidación de nuevas fuerzas políticas y los consecuentes problemas de representación que generan al limitar la oferta electoral. La segunda atiende al conjunto de reglas y prácticas, en particular, la organización territorial y descentralizada de los partidos y sus patrones de competencia interna, que contribuyen a la creación de una clase política ensimismada y a la vez fragmentada que administra pobremente los intereses sociales que representa. En la sección final, se se alan algunas de las paradojas que sugiere el análisis realizado, en particular respecto de los argumentos que, para mejorar la representación, abogan a favor de un contacto más estrecho entre representantes y representados, la personalización del voto y la democracia interna en los partidos. ABSTRACT: This article examines the crisis of representation of the Argentine political parties by highlighting two dimensions: the relationship between parties and the electorate and the relationship between parties and government. The first dimension relates to the restrictions that the federal electoral system poses to the consolidation of new political forces. Problems of representation arise because the electoral system limits the electoral offer. The second dimension deals with party organisation, in particular, its decentralised and territorial nature and the rules that structure internal party competition. These features contribute to create an auto referential political class that poorly administrates the interests it represents. In the final section the article deals with some of the paradoxes that stem from the analyses, specially those raised by the arguments in favour of a closer relationship between representatives and represented, the personal vote and the party’s internal democracy.

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Decay Rates of Metastable States in Cubic Potential by Variational Perturbation Theory
H. Kleinert,I. Mustapic
Physics , 1995, DOI: 10.1142/S0217751X96002029

Abstract: Variational perturbation theory is used to determine the decay rates of metastable states across a cubic barrier of arbitrary height. For high barriers, a variational resummation procedure is applied to the complex energy eigenvalues obtained from a WKB expansion; for low barriers, the variational resummation procedure converts the non-Borel-summable Rayleigh-Schr\"o\-din\-ger expansion into an exponentially fast convergent one. The results in the two regimes match and yield very accurate imaginary parts of the energy eigenvalues. This is demonstrated by comparison with the complex eigenvalues from solutions of the Schr\"odinger equation via the complex-coordinate rotation method.

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Ultrasound Grade of Liver Steatosis Is Independently Associated with the Risk of Metabolic Syndrome
Bozo Radic,Ivica Grgurevic,Marko Lucijanic,Sanda Mustapic,Sead Ziga,Srecko Marusic,Tomislav Bokun,Vladimir Matic,Zarko Babic
- , 2018, DOI: 10.1155/2018/8490242

Abstract:

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Extracellular vesicle-associated Aβ mediates trans-neuronal bioenergetic and Ca2+-handling deficits in Alzheimer’s disease models
Caitlin Suire,Chinmoyee Maharana,Dimitrios Kapogiannis,Dong Liu,Emmette R Hutchison,Erez Eitan,Gregory A Jicha,James Comotto,Kenneth W Witwer,Krisztina Marosi,Maja Mustapic,Mark P Mattson,Saket M Nigam,Vasiliki Machairaki
- , 2016, DOI: 10.1038/npjamd.2016.19

Abstract: Alzheimer’s disease (AD) is an age-related neurodegenerative disorder in which aggregation-prone neurotoxic amyloid β-peptide (Aβ) accumulates in the brain. Extracellular vesicles (EVs), including exosomes, are small 50–150？nm membrane vesicles that have recently been implicated in the prion-like spread of self-aggregating proteins. Here we report that EVs isolated from AD patient cerebrospinal fluid and plasma, from the plasma of two AD mouse models, and from the medium of neural cells expressing familial AD presenilin 1 mutations, destabilize neuronal Ca2+ homeostasis, impair mitochondrial function, and sensitize neurons to excitotoxicity. EVs contain a relatively low amount of Aβ but have an increased Aβ42/ Aβ40 ratio; the majority of Aβ is located on the surface of the EVs. Impairment of lysosome function results in increased generation of EVs with elevated Aβ42 levels. EVs may mediate transcellular spread of pathogenic Aβ species that impair neuronal Ca2+ handling and mitochondrial function, and may thereby render neurons vulnerable to excitotoxicity

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Heritable Influence of DBH on Adrenergic and Renal Function: Twin and Disease Studies
Dalal N. Pasha, Jason T. Davis, Fangwen Rao, Yuqing Chen, Gen Wen, Maple M. Fung, Manjula Mahata, Kuixing Zhang, Danuta Trzebinska, Maja Mustapic, C. Makena Hightower, Michael S. Lipkowitz, Ming Ji, Michael G. Ziegler, Caroline M. Nievergelt, Daniel T. O'Connor
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0082956

Abstract: Background Elevated sympathetic activity is associated with kidney dysfunction. Here we used twin pairs to probe heritability of GFR and its genetic covariance with other traits. Methods We evaluated renal and adrenergic phenotypes in twins. GFR was estimated by CKD-EPI algorithm. Heritability and genetic covariance of eGFR and associated risk traits were estimated by variance-components. Meta-analysis probed reproducibility of DBH genetic effects. Effect of DBH genetic variation on renal disease was tested in the NIDDK-AASK cohort. Results Norepinephrine secretion rose across eGFR tertiles while eGFR fell (p<0.0001). eGFR was heritable, at h2 = 67.3±4.7% (p = 3.0E-18), as were secretion of norepinephrine (h2 = 66.5±5.0%, p = 3.2E-16) and dopamine (h2 = 56.5±5.6%, p = 1.8E-13), and eGFR displayed genetic co-determination (covariance) with norepinephrine (ρG = ？0.557±0.088, p = 1.11E-08) as well as dopamine (ρG = ？0.223±0.101, p = 2.3E-02). Since dopamine β-hydroxylase (DBH) catalyzes conversion of dopamine to norepinephrine, we studied functional variation at DBH; DBH promoter haplotypes predicted transcriptional activity (p<0.001), plasma DBH (p<0.0001) and norepinephrine (p = 0.0297) secretion; transcriptional activity was inversely (p<0.0001) associated with basal eGFR. Meta-analysis validated DBH haplotype effects on eGFR across 3 samples. In NIDDK-AASK, we established a role for DBH promoter variation in long-term renal decline rate (GFR slope, p = 0.003). Conclusions The heritable GFR trait shares genetic determination with catecholamines, suggesting new pathophysiologic, diagnostic and therapeutic approaches towards disorders of GFR as well as CKD. Adrenergic activity may play a role in progressive renal decline, and genetic variation at DBH may assist in profiling subjects for rational preventive treatment.

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