Objective: To observe the therapeutic effect of three-dimensional conformal radiotherapy combined with Tegafur Gimeracil and Oteracil Potassium in the treatment of locally advanced esophageal cancer. Method: The patients with locally advanced esophageal cancer admitted to our hospital were randomly divided into observation group and control group. The control group was treated with three-dimensional conformal radiotherapy alone; the observation group, three-dimensional conformal radiotherapy combined with tegafur was used. Result: In the observation group, the patient’s disease control rate was 89.74%, and in the control group, the patient’s disease control rate was 71.79%. The results of the two groups were compared and the difference was statistically significant (p < 0.05). In the observation group, the patient’s leukopenia rate was 38.46%, the thrombocytopenia rate was 35.90%, the incidence of nausea and vomiting was 53.85%, and the quality of life was (85.20 ± 1.59) points. There was no significant difference (p > 0.05) compared with the control group. The local recurrence rate of the observation group was 10.26%, and the difference was significant compared with the control group (p < 0.05). Conclusion: The treatment of locally advanced esophageal cancer by three-dimensional conformal radiotherapy combined with Tegafur Gimeracil and Oteracil Potassium treatment can effectively improve the control rate of the disease, and its clinical application value is very significant.
Cite this paper
Yan, X. and Yu, H. (2019). Therapeutic Effect of Three-Dimensional Conformal Radiotherapy Combined with Tegafur Gimeracil and Oteracil Potassium in the Treatment of Locally Advanced Esophageal Cancer. Open Access Library Journal, 6, e5303. doi: http://dx.doi.org/10.4236/oalib.1105303.
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