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Measles Outbreak Investigation in Pweto Health Zone—Haut-Katanga Province, DR of the Congo, 2018

DOI: 10.4236/oalib.1106863, PP. 1-14

Subject Areas: Epidemiology, Infectious Diseases

Keywords: Measles, Outbreak Investigation, Outbreak Management, Pweto

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Background: Sub-Saharan Africa reports repeated outbreaks of measles, a vaccine-preventable disease, which is notifiable under the Integrated Disease Surveillance and Response (IDSR) strategy in Democratic Republic of Congo (DRC). DRC has reported several outbreaks of measles in the last three years. Poor immunization coverage and weak health systems have been related with measles and other vaccination-preventable diseases’ outbreaks. The DRC has committed to eliminating measles by 2020. In this respect, we investigated one of the outbreaks that occurred in Pweto health zone (HZ), Haut-Katanga province, to describe the outbreak and identify risk factors. Methods: A cross-sectional study was designed to investigate a measles outbreak in Pweto health zone (HZ), Haut-Katanga province. Data entry and analysis were performed using EPI-Info version and MS-Microsoft Excel. Findings: In seven months’ time, four health areas affected by a measles outbreak in Pweto health zone reported 116-suspected cases and 13 deaths. The cumulative attack rate of 42.3/100,000 population and case fatality rate (CFR) of 11.2% were recorded. Of these, 112 (96.5%) cases were ≤15 years of age, and 93 (80.2%) were zero dose of measles vaccine. Although, all age groups were concerned, under five years old were the most affected with 84 cases (72.4%). In response to the outbreak, a response immunization was organized with the support of MSF at the week 25 of the epidemic, when the epidemic curve started to decline. A response immunization involving 46,205 children from 6 to 59 was implemented and overall coverage of 99% (range: 95% - 105%) was achieved. Case management with vitamin A supplementation, active case search, routine immunization improvement and health education were some of the activities carried out to curb the outbreak. Conclusion: This confirmed measles outbreak was caused by failure to vaccinate (80.2% unvaccinated cases). Poor surveillance sensitivity and the community attitude about measles contributed to its spreading. Strengthening routine immunization, improving surveillance system and communication for behaviour change are required.

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Kwete, G. K. W. , Yao, E. and Numbi, J. K. W. (2020). Measles Outbreak Investigation in Pweto Health Zone—Haut-Katanga Province, DR of the Congo, 2018. Open Access Library Journal, 7, e6863. doi:


[1]  Geremew, T.T., Gezie, L.D. and Abejie, A.N. (2019) Geographical Variation and Associated Factors of Childhood Measles Vaccination in Ethiopia: A Spatial and Multilevel Analysis. BMC Public Health 19, 1194.
[2]  World Health Organization Regional Office for Africa (2015) African Regional Guidelines for Measles and Rubella Surveillance. Geneva.
[3]  World Health Organization (WHO) (1997) Guidelines for Epidemic Preparedness and Response to Measles Outbreaks. World Health Organization, Geneva.
[4]  Okonko, I.O., Nkang, A.O., Udeze, A.O., Adedeji, A.O., Ejembi, J., Onoja, B.A., Garba, K.N., et al. (2013) Global Eradication of Measles: A Highly Contagious and Vaccine Preventable Disease—What Went Wrong in Africa? Journal of Cell and Animal Biology, 3, 119-140.
[5]  World Health Organization (2012) Global Measles and Rubella Strategic Plan: 2012-2020. World Health Organization, Geneva.
[6]  Smith, R., Woodward, D., Acharya, A., Beaglehole, R. and Drager, N. (2004) Communicable Disease Control: A “Global Public Good” Perspective. Health Policy and Planning, 19, 271-278.
[7]  World Health Organization (2009) Measles Vaccines: WHO Position Paper. The Weekly Epidemiological Record, 35, 349-360.
[8]  Ministry of Health of Democratic Republic of Congo (2012) Follow-Up Campaign against Measles, Action Plan 2010. Unpublished Results.
[9]  World Health Organization African Region (2011) Measles Outbreaks and Progress towards Meeting Measles Pre-Elimination Goals. The Weekly Epidemiological Record, 13, 129-136.
[10]  World Health Organization (2018) Measles Fact Sheet 2018. WHO, Geneva.
[11]  Kalil, F.S., Gemeda, D.H., Bedaso, M.H. and Wario, S.K. (2020) Measles Outbreak Investigation in Ginnir District of Bale Zone, Oromia Region, Southeast Ethiopia, May 2019. The Pan African Medical Journal, 36, 20.
[12]  World Health Organization (2019) Measles Fact Sheet: May 2019. WHO, Geneva.
[13]  Center for Disease Control and Prevention (2019) Measles Update. CDC.
[14]  Ducomble, T. and Gignoux, E. (2020) Learning from a Massive Epidemic: Measles in DRC. The Lancet Infectious Diseases, 20, 542.
[15]  Belda, K., Tegegne, A.A., Mersha, A.M., Bayenessagne, M.G., Hussein, I. and Bezabeh, B. (2017) Measles Outbreak Investigation in Guji Zone of Oromia Region, Ethiopia. The Pan African Medical Journal, 27, 9.
[16]  Mancini, S., Coldiron, M.E., Ronsse, A., Ilunga, B.K., Porten, K. and Grais, R.F. (2014) Description of a Large Measles Epidemic in Democratic Republic of Congo, 2010-2013. Conflict and Health, 8, 9.
[17]  Hyde, T.B., Dayan, G.H., Langidrik, J.R., Nandy, R., Edwards, R., Briand, K., O’Leary, M.J., et al. (2006) Measles Outbreak in the Republic of the Marshall Islands, 2003. International Journal of Epidemiology, 35, 299-306.
[18]  de Oliveira, S.A., Soares, W.N., Dalston, M.O., de Almeida, M.T. and Costa, A.J. (1995) Clinical and Epidemiological Findings during a Measles Outbreak Occurring in a Population with a High Vaccination Coverage. Revista da Sociedade Brasileira de Medicina Tropical, 28, 339-343.
[19]  EHNRI, Federal Democratic Republic of Ethiopia (2012) Guideline on Measles Surveillance and Outbreak Management. Addis Ababa.
[20]  Ntshoe, G.M., McAnerney, J.M., Archer, B.N., Smit, S.B., Harris, B.N., Tempia, S., Blumberg, L.H., et al. (2013) Measles Outbreak in South Africa: Epidemiology of Laboratory-Confirmed Measles Cases and Assessment of Intervention, 2009-2011. PLoS ONE, 8, e55682.
[21]  Aragaw, M. and Tilay, T. (2012) Measles Outbreak in Simada District, South Gondar Zone, Amhara Region, May-June 2009: Immediate Need for Strengthened Routine and Supplemental Immunization Activities (SIAs). Ethiopian Journal of Health Development, 26, 115-118.
[22]  Mandomando, I., Naniche, D., Pasetti, M.F., Cuberos, L., Sanz, S., Vallès, X., Levine, M.M., et al. (2011) Assessment of the Epidemiology and Burden of Measles in Southern Mozambique. The American Journal of Tropical Medicine and Hygiene, 85, 146-151.
[23]  Rice, A.L., Sacco, L., Hyder, A. and Black, R.E. (2000) Malnutrition as an Underlying Cause of Childhood Deaths Associated with Infectious Diseases in Developing Countries. Bulletin of the World Health Organization, 78, 1207-1221.
[24]  Kambarami, R.A., Nathoo, K.J., Nkrumah, F.K. and Pirie, D.J. (1991) Measles Epidemic in Harare, Zimbabwe, despite High Measles Immunization Coverage Rates. Bulletin of the World Health Organization, 69, 213.
[25]  Nandy, R., Handzel, T., Zaneidou, M., Biey, J., Coddy, R.Z., Perry, R. and Cairns, L. (2006) Case-Fatality Rate during a Measles Outbreak in Eastern Niger in 2003. Clinical Infectious Diseases, 42, 322-328.


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