Background: In October 2016, a cholera outbreak occurred in the Cape Coast Metropolis, Central Region, Ghana, spreading rapidly in peri-urban communities. The Researchers conducted a descriptive analysis of surveillance data to examine the epidemiological characteristics of this outbreak. Methods: The retrospective analysis covered cholera cases from October to December 2016, focusing on onset date, age, sex, rapid diagnostic test (RDT) results, and residence. Pearson’s chi-square/Fisher’s exact tests were used to find associations. Results: The outbreak comprised 731 cases, resulting in an overall attack rate of 67 per 100,000 population, with no reported fatalities. The epidemic curve exhibited multiple progressive peaks, indicative of a person-to-person transmission outbreak. The mean age of affected individuals was 23, and 40% of cases occurred in the 15 - 24 age group. There was no significant gender difference (p = 0.619). Cape Coast Metropolis accounted for nearly 90% of cases, while Abura-Asebu-Kwamankese (AAK) and Komenda-Edina-Eguafo Abirem (KEEA) contributed to the remaining 10%. RDT results were significantly associated with bacterial culture (p < 0.001), and sex was linked to final case classification (p = 0.004). Conclusion: The Cholera outbreak was attributed to poor sanitation, hygiene, and water/food quality. Future interventions should prioritize addressing environmental and behavioural factors to prevent similar outbreaks in the future.
Cite this paper
Acheampong, G. K. , Owusu, I. , Zumah, F. , Akyereko, E. and Mpangah, R. A. (2023). Retrospective Study of an Epidemic Vibrio cholerae in the Central Region of Ghana: An Evidence from Surveillance Data. Open Access Library Journal, 10, e603. doi: http://dx.doi.org/10.4236/oalib.1110603.
Debes, A.K., et al. (2016) Clinical and Environmental Surveillance for Vibrio cholerae in Resource Constrained Areas: Application during a 1-Year Surveillance in the Far North Region of Cameroon. American Journal of Tropical Medicine and Hygiene, 94, 537-543. https://doi.org/10.4269/ajtmh.15-0496
Dziedzom, A.K. (2015) Cholera Outbreaks in Greater Accra Region, Ghana: The Economic Costs to the Health Facility and Affected Households. University of Ghana, Accra.
Constantin de Magny, G., et al. (2008) Environmental Signatures Associated with Cholera Epidemics. Proceedings of the National Academy of Sciences of the United States of America, 105, 17676-17681.
National Population Council (2011) Profile of the Central Region. 4668.
https://unstats.un.org/unsd/demographic-social/census/documents/Nepal/Nepal-Census-2011-Vol1.pdf
Ohene, S.-A., Klenyuie, W. and Sarpeh, M. (2016) Assessment of the Response to Cholera Outbreaks in Two Districts in Ghana. Infectious Diseases of Poverty, 5, Article No. 99. https://doi.org/10.1186/s40249-016-0192-z
Opare, J.K., Ohuabunwo, C., Afari, E., Wurapa, F., Sackey, S.O., Der, J., Afakye, K. and Odei, E. (2012) Outbreak of Cholera in the East Akim Municipality of Ghana Following Unhygienic Practices by Small-Scale Gold Miners, November 2010. Ghana Medical Journal, 46, 11.
Shittu, O.B., Akpan, I., Popoola, T.O.S., Oyedepo, J.A. and Ogunshola, E. O. (2010) Epidemiological Features of a GIS-Supported Investigation of Cholera Outbreak in Abeokuta, Nigeria. Journal of Public Health and Epidemiology, 2, 152-162.
Cholera Surveillance: Detecting and Reporting Cases (2015) Johns Hopkins Bloomberg School of Public Health 615 N.
https://www.stopcholera.org/sites/default/files/cholera_surveillance_detecting_and_reporting_cases_0.pdf
Sanchez-Padilla, E., Carrillo-Santisteve, P. and Luquero, F.J. (2009) Evaluation of the Cholera Surveillance System in Guinea Bissau. WHO Collaborating Centre for Epidemiology Research and Response to Emerging Diseases.
https://plateformecholera.info/sites/default/files/2022-11/8-GNB_2009_SLL_UNICEF_ECSS_EN.pdf
Godana, W. and Mengistie, B. (2013) Determinants of Acute Diarrhoea among Children under Five Years of Age in Derashe District, Southern Ethiopia. Rural and Remote Health, 13, Article No. 2329. https://doi.org/10.22605/RRH2329
Tambe, A.B., Nzefa, L.D. and Nicoline, N.A. (2015) Childhood Diarrhea Determinants in Sub-Saharan Africa: A Cross Sectional Study of Tiko-Cameroon. Challenges, 6, 229-243. https://doi.org/10.3390/challe6020229
Barzilay, E.J., et al. (2013) Cholera Surveillance during the Haiti Epidemic—The First 2 Years. New England Journal of Medicine, 368, 599-609.
https://doi.org/10.1056/NEJMoa1204927
McGarvey, S.T., et al. (2008) Community and Household Determinants of Water Quality in Coastal Ghana. Journal of Water and Health, 6, 339-349.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624763/pdf/nihms412728.pdfNkukpornu
Nkukpornu, A. (2015) Social Marketing: Using the Health Belief Model. International Journal of Behavioural and Healthcare Research, 6, 2018.
https://afribary.com/works/social-marketing-using-the-health-belief-model-for-the-prevention-of-cholera-in-ghana
Fink, G., Günther, I. and Hill, K. (2011) The Effect of Water and Sanitation on Child Health: Evidence from the Demographic and Health Surveys 1986-2007. International Journal of Epidemiology, 40, 1196-1204.
https://doi.org/10.1093/ije/dyr102
Siziya, S., Muula, A.S. and Rudatsikira, E. (2013) Correlates of Diarrhoea among Children below the Age of 5 Years in Sudan. African Health Sciences, 13, 376-383.
https://doi.org/10.4314/ahs.v13i2.26
Dalhat, M.M., et al. (2014) Descriptive Characterization of the 2010 Cholera Outbreak in Nigeria. BMC Public Health, 14, Article No. 1167.
https://doi.org/10.1186/1471-2458-14-1167
Singh, J.P., Gupta, S.B., Shrotriya, V.P. and Singh, P.N. (2013) Study of Nutritional Status among under Five Children Attending out Patient Department at a Primary Care Rural Hospital, Bareilly (UP). Scholars Journal of Applied Medical Sciences, 1, 769-773.