%0 Journal Article
%T Uso t¨®pico da adrenalina em diferentes concentra£¿£¿es na cirurgia endosc¨®pica nasal
%A Sarmento Junior
%A Krishnamurti Matos de Araujo
%A Tomita
%A Shiro
%A K¨®s
%A Arthur Octavio de ¨¢vila
%J Revista Brasileira de Otorrinolaringologia
%D 2009
%I Scientific Electronic Library Online
%R 10.1590/S0034-72992009000200020
%X the ideal adrenaline concentration remains unknown. aim: compare topical adrenaline solutions in different concentrations. study design: prospective, double blind, randomized trial. patients and methods: 49 patients divided in 3 groups underwent endoscopic sinus surgery, using only topical solutions of adrenaline in different concentrations (1:2,000, 1:10,000 and 1:50,000). we compared the duration of surgery, intra-operative bleeding, plasmatic levels of catecholamines, hemodynamic parameters and changes in heart rhythm. results: surgery time was shorter in the group using adrenaline 1:2,000, which also showed less bleeding in all evaluations (objective and subjective - p < 0.0001). plasmatic levels of epinephrine rose in all groups, more sharply in the 1:2,000 group. there was a trend towards elevation of blood pressure in the groups using adrenaline 1:2,000 and 1:10,000, with a greater occurrence of hypertensive peaks. discussion: we found a very significance bleeding difference favoring the 1:2,000. the blood pressure elevation in the 1:2,000 and 1:10,000 groups was progressive but very slow throughout the procedure, which could be associated with the anesthesia technique. conclusion: we favor the use of topical adrenalin 1:2,000 due to a clear superiority in hemostasis. further investigation is needed to corroborate our findings.
%K paranasal sinus diseases
%K epinephrine
%K hemostasis surgical
%K norepinephrine
%K nasal polyps.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0034-72992009000200020&lng=en&nrm=iso&tlng=en