%0 Journal Article
%T The side-effects of different doses of iron sulfate on women of reproductive age: a randomized double-blind, placebo-controlled study
%A Machado
%A Katia Maria de Melo
%A Ferreira
%A Luiz Oscar Cardoso
%A Souza
%A Ariani Impieri de
%A Diniz
%A Alcides da Silva
%J Revista Brasileira de SaĻēde Materno Infantil
%D 2011
%I Instituto Materno Infantil de Pernambuco
%R 10.1590/S1519-38292011000300008
%X objectives: to identify side effects of the use of different doses of iron sulfate (is). methods: an eight-week randomized, double blind, placebo-controlled trial was carried out involving 727 women aged 20-49 years between october 2005 and october 2006. the women were randomly allocated into eight groups with daily or twice-weekly doses administered during or in between meals. the information was obtained by weekly telephone contact. analysis involved comparison of the proportion of complaints from the different groups. results: of 726 women initially selected, 74.2% completed eight weeks of follow up. in the regimens containing is 95.2% of women reported gastrointestinal complaints. more complaints were reported for daily doses than for ones (p <0.001). those taken between meals were associated with more nausea than those taken during meals (p<0.001). of the 95 women who withdrew from the experiment, 88.4% belonged to the is group and diarrhea was the main complaint (29.8%). conclusions: the use of iron sulfate was associated with gastrointestinal side effects, especially when taken daily and diarrhea was the main complaint associated with is.
%K iron sulfate
%K women's health
%K anemia
%K iron-deficiency
%K iron.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S1519-38292011000300008&lng=en&nrm=iso&tlng=en