%0 Journal Article
%T Utilidad del ¨ªndice HOMA-IR con una sola determinaci¨®n de insulinemia para diagnosticar resistencia insul¨ªnica
%A Hern¨¢ndez Yero
%A Jos¨¦ Arturo
%A Tuero Iglesias
%A ¨¢ngela
%A Vargas Gonz¨¢lez
%A David
%J Revista Cubana de Endocrinolog£¿-a
%D 2011
%I Scientific Electronic Library Online
%X introduction: homa-ir index is a simple and not much invasive procedure allowing by a validated and well established formula to specify exactly a value expression of insulin resistance. to estimate the homa-ir index with an only numerical value of insulinemia could to present a greater variability, something that could be solved with at least the mean of three insulinemias, according to original formula. en some studies it is habitual to perform it with a single insulinemia determination. thus, we conducted a study in patients presenting type 2 diabetes and to compare the results as regards the sensitivity and specificity with a single blood determination for insulinemia and glycemia. objectives: to assess the sensitivity and specificity of each of insulinemia determinations performed each 5 min versus the mean of these determinations during the application of formula for homa-ir index. methods: sixty patients diagnosed with type 2 diabetes attended in the center for diabetic care of la habana were studied. they had a diabetes course time lower than 5 years as average with predominance of body excess weight recruited during 6 months in a consecutive way and the carrying out of fasting insulinemias and glycemias determinations by trocar and venous blood extraction at 0,5 and 10 min for a calculation of mathews's hemostatic model known as homa-ir. results: a 88,3 % had a homa-ir greater than 3,2. the sensitivity of a single sample of insulinemia, although high to confirm the insulin resistance diagnosis, it is variable and specificity of one of samples was low with a 14%. there is an appropriate concordance among the positive predictor values with sensitivity and the negative predictive values with the test specificity. conclusions: a single insulinemia determination to study homa-ir is useful in daily practice, although it is necessary much accuracy to apply the original formula for a better reproducibility.
%K homa-ir
%K insulin resistance
%K type 2 diabetes.
%U http://scielo.sld.cu/scielo.php?script=sci_abstract&pid=S1561-29532011000200002&lng=en&nrm=iso&tlng=en