%0 Journal Article
%T Factores predictores de met¨¢stasis ganglionar en el carcinoma diferenciado de tiroides
%A Falco
%A Jorge E
%A Otero Mu£¿oz
%A Alvaro
%A Montesinos
%A Manuel R
%J Revista argentina de cirug£¿-a
%D 2012
%I Scientific Electronic Library Online
%X background: reliable prognostic factors of lymph node met¨¢stasis are needed to adapt initial surgical treatment of patients with differentiated thyroid carcinoma. objetive: to determine the frequency and predictive factors associated with lymph node met¨¢stasis in patients operated on for differentiated thyroid carcinoma. setting: pr¨ªvate practice. design: retrospective observational. popuation: between january 2000 and august 2010, 600 patients with 639 tumours (39 bilateral) underwent total thyroidectomy and therapeutic neck dissection only when there was biopsy proved lymph node met¨¢stasis. method: review of clinical records and pathological reports. resuts: 145 patients (22.7 %) had histologically positive lymph nodes. multivariate analysis showed that lessthan 45 years (p = 0.001), palpable adenopathy (p = 0.0001), multicentricity (p = 0.005) and extracapsular invasi¨®n (p = 0.0001) were independent risk factors of lymph node met¨¢stasis. these factors, together, had high specificity (97 %) but low sensibility (40 %). met¨¢stasis in jugular lymph nodes with normal central nodes (skip met¨¢stasis) was found in 29 (5.54 %) cases. concusions: even though some of the factors studied proved to be of prognostic valu¨¦, additional variables are needed to better define surgical management.
%K gland
%K thyroid
%K neoplasm
%K met¨¢stasis lymph node.
%U http://www.scielo.org.ar/scielo.php?script=sci_abstract&pid=S2250-639X2012000200002&lng=en&nrm=iso&tlng=en