%0 Journal Article
%T Agonist and antagonist binding to the nuclear vitamin D receptor: dynamics, mutation effects and functional implications
%A Sepideh Yaghmaei
%A Christopher Roberts
%A Rizi Ai
%A Mathew T Mizwicki and Chia-en A Chang
%J In Silico Pharmacology
%D 2013
%I Springer
%R 10.1186/2193-9616-1-2
%X The MD methodology applied herein provides an in silico foundation to be expanded upon to better understand the intrinsic flexibility of the VDR and better understand key side-chain and backbone movements involved in the bimolecular interaction between the VDR and its¡¯ ligands.
%K Nuclear vitamin D receptor
%K Vitamin D3
%K 1¦Á
%K 25(OH)2-vitamin D3
%K Antagonist
%K Molecular dynamics
%K Helix 12
%K Conformational ensemble
%U http://www.in-silico-pharmacology.com/content/1/1/2/abstract