%0 Journal Article
%T Does Hyponatremia have a Value in the Diagnosis of Extrapulmonary Tuberculosis in HIV-1 Infected Patients in Cambodia?
%A Lut Lynen
%A Sok Phan
%A Suos Prem Prey
%A Thai Sopheak
%A Joseph Harwell
%A Marleen Boelaert
%A Olivier Koole
%A Robert Colebunders
%J The Open Infectious Diseases Journal
%D 2007
%I Bentham Open
%R 10.2174/1874279300701010001]
%X Hyponatremia is a frequent finding in hospitalised HIV-patients. The diagnosis of extra-pulmonary tuberculosis (EPTB) is difficult in resource-limited settings, causing delays in treatment. In this cross-sectional study based on hospital chart review in a charity hospital in Cambodia we found that hyponatremia (serum sodium < 134 meq/L) was significantly associated with a diagnosis of EPTB in HIV-positive adults. Our findings suggest that hyponatremia in patients with advanced stage of HIV disease should trigger a diagnostic work-up for EPTB.
%U http://www.benthamscience.com/open/toidj/articles/V001/1TOIDJ.htm