%0 Journal Article %T Adenosine Kinase Expression Modulates Expression of Myelin Proteolipid Protein %A Natalie Lai-man Wu and Detlev Boison %J The Open Neuroscience Journal %D 2007 %I %R 10.2174/1874082000701010015] %X Adenosine is known to regulate myelination in vitro. Here we tested the hypothesis that adenosine, regulated by adenosine kinase (ADK), might regulate myelin-specific protein expression and myelination in vivo. We demonstrate that transgenic overexpression of ADK, which reduces adenosine in mouse brain, results in increased levels of myelin proteolipid protein. %U http://www.benthamscience.com/open/toneurj/articles/V001/15TONEURJ.htm