%0 Journal Article
%T Crystallization and Preliminary X-Ray Crystallographic Studies of a Myotoxic Lys49-phospholipase A2 from Bothrops jararacussu Venom Complexed with ¦Á-Tocopherol Inhibitorm
%A Bothrops jararacussuAgnes A.S. Takeda
%A Juliana I. dos Santos
%A Daniela P. Marchi-Salvador
%A Andreimar M. Soares and Marcos R.M. FontesBothrops jararacussu
%J The Open Crystallography Journal
%D 2008
%I 
%R 10.2174/1874846500801010006]
%X Bothropstoxin I (BthTX-I), a non-catalytic and myotoxic Lys49-PLA2 from Bothrops jararacussu venom, has been crystallized alone and complexed with ¦Á-tocopherol inhibitor. These crystals have been shown to diffract X-rays between 2.17 and 1.83   resolution. The BthTX-I/¦Á-tocopherol complex crystals are not isomorphous with those of the native protein. This suggests the inhibitor binding has lead to changes in the quaternary structure and a different conformation may have been obtained.
%U http://www.benthamscience.com/open/tocryj/articles/V001/6TOCRYJ.htm