%0 Journal Article %T Helicobacter Pylori Infection and Upper Gastrointestinal Disease %A Marina Dini %A %A Dobrila Stankovi or evi %A %A Gordana Tasi %A %A Branislava Koci %A %A Milena Bogdanovi %J Acta Facultatis Medicae Naissensis %@ 2217-2521 %D 2012 %I %R 10.2478/v10283-012-0001-y %X Helicobacter pylori infection is one of the most common bacterial infections in humans, being present in over a half of the world population. Helicobacter pylori infection, by itself, does not necessarily produce the symptoms of gastrointestinal tract diseases, but certainly presents a risk for their development. The clinical outcome of Helicobacter pylori infection depends on the interaction of numerous factors: the virulence of a bacterial strain, genetic predisposition and premorbid host conditions, as well as the environmental factors. Accordingly, a diagnosis of Helicobacter pylori infection will be of clinical relevance only if it is necessary to establish the cause of a disease associated with this infection. Thus, a thorough knowledge of the diseases associated with Helicobacter pylori infection is a key factor in any relevant assessment of the need for eradication therapy. %K Helicobacter pylori %K disease %U http://versita.metapress.com/content/mp818u748k377480/?p=414a9bc5112444e4812cde838ede10b3&pi=0