%0 Journal Article
%T Studies on the hepatic antioxidant defense system in ¦Ë cyhalothrin-induced oxidative stress in fresh water tilapia (Oreochromis mossambicus)
%A R Parthasarathy
%A J Joseph
%J African Journal of Environmental Science and Technology
%D 2011
%I 
%X The present study was undertaken to determine the effects of ¦Ë cyhalothrin-induced oxidative stress in fresh water tilapia (Oreochromis mossambicus) with respect to changes in the levels of lipid peroxidation [LPO], reduced glutathione [GSH], glutathione-dependent antioxidant enzymes (glutathione peroxidase [GPX] and glutathione-S-transferase [GST]) and antiperoxidative enzymes (catalase [CAT] and superoxide dismutase [SOD]). Significant (P<0.05) elevation in the level of lipid peroxidation was observed in ¦Ë cyhalothrin-intoxicated fishes as compared to controls. A concomitant (P<0.05) decline in hepatic antioxidant status was also observed. The results of the present investigation have indicated that the tissue antioxidant defense system is operating at a lower rate despite increased ¦Ë cyhalothrin-induced oxidative stress.
%U http://www.ajol.info/index.php/ajest/article/view/72039