%0 Journal Article
%T Production of (2R,3S)-2-Benzamidomethyl-3-Hydroxybutanoates by Immobilized Plant Cells of Parthenocissus Tricuspidata
%A Kei Shimoda
%A Naoji Kubota
%A Hatsuyuki Hamada
%A Tatsunari Kobayashi
%A Hiroki Hamada
%A Siddiqi M. Shafi and Nobuyoshi Nakajima
%J Biochemistry Insights
%D 2012
%I 
%X Incubation of methyl 2-benzamidomethyl-3-oxobutanoate with cultured plant cells of Parthenocissus tricuspidata for 2 days afforded methyl (2R,3S)-2-benzamidomethyl-3-hydroxybutanoate with 100% de and 99% ee in 51% yield. The use of immobilized cells of P. tricuspidata in calcium alginate gel improved the yield of the product (95% yield) with 100% de and 99% ee. The immobilized cells of P. tricuspidata maintained the high potential for the reduction of methyl 2-benzamidomethyl-3-oxobutanoate (85% yield) after 5 times of usage.
%U http://www.la-press.com/production-of-2r3s-2-benzamidomethyl-3-hydroxybutanoates-by-immobilize-article-a1256