%0 Journal Article
%T Quetiapine Induced Acute Dystonia in a Patient with History of Severe Head Injury
%A Robert G. Bota and Joanne W. Witkowski
%J Rehabilitation Process and Outcome
%D 2012
%I 
%R 10.4137/RPO.S3626
%X A patient with a history of severe head injury 10 years ago regained ability to walk after years of being bound to a wheelchair. During the last psychiatric hospitalization, quetiapine was increased to therapeutic dose using a normal titration. As a result the patient developed dystonia of multiple muscle groups requiring 4 days of hospitalization for remittance of symptoms. In this paper, we take a close look at the literature concerning extrapiramidal symptoms (EPS) in this context, and we suggest that in patients with a history of head injury, it is warranted to consider a slower titration of antipsychotic medications, including ones that are considered having a lower risk of EPS such as quetiapine.
%U http://www.la-press.com/quetiapine-induced-acute-dystonia-in-a-patient-with-history-of-severe--article-a1828