%0 Journal Article
%T A Microbial Metagenome (Leucobacter sp.) in Caenorhabditis Whole Genome Sequences
%A Riccardo Percudani
%J Bioinformatics and Biology Insights
%D 2012
%I 
%R 10.4137/BBI.S11064
%X DNA of apparently recent bacterial origin is found in the genomic sequences of Caenorhabditis angaria and Caenorhabditis remanei. Here we present evidence that the DNA belongs to a single species of the genus Leucobacter (high-GC Gram+ Actinobacteria). Metagenomic tools enabled the assembly of the contaminating sequences in a draft genome of 3.2 Mb harboring 2,826 genes. This information provides insight into a microbial organism intimately associated with Caenorhabditis as well as a solid basis for the reassignment of 3,373 metazoan entries of the public database to a novel bacterial species (Leucobacter sp. AEAR). The application of metagenomic techniques can thus prevent annotation errors and reveal unexpected genetic information in data obtained by conventional genomics.
%U http://www.la-press.com/a-microbial-metagenome-leucobacter-sp-in-caenorhabditis-whole-genome-s-article-a3557