%0 Journal Article
%T Subendocardial Fibrosis in Left Ventricular Hypertrabeculation-Cause or Consequence?
%A J. Ker
%A L. Du Toit-Prinsloo
%A W.F.P. Van Heerden and G. Saayman
%J Clinical Medicine Insights: Cardiology
%D 2012
%I 
%R 10.4137/CMC.S6507
%X Left ventricular noncompaction has been classified as a primary cardiomyopathy with a genetic origin. This condition is morphologically characterized by a thickened, two-layered myocardium with numerous prominent trabeculations and deep, intertrabecular recesses. Recently, it has become clear that these pathological characteristics extend across a continuum with left ventricular hypertrabeculation at one end of the spectrum. The histological findings include areas of interstitial fibrosis. We present a case of left ventricular hypertrabeculation which presented as sudden infant death syndrome. Histologically areas of subendocardial fibrosis was prominent and we propose that this entity may be a hidden cause of arrhythmic death in some infants presenting as sudden infant death syndrome., with areas of subendocardial fibrosis as possible arrhythmogenic foci.
%U http://www.la-press.com/subendocardial-fibrosis-in-left-ventricular-hypertrabeculation-cause-o-article-a2447