%0 Journal Article
%T Exercise training improves fasting glucose control
%A Norton L
%A Norton K
%A Lewis N
%J Open Access Journal of Sports Medicine
%D 2012
%I Dove Medical Press
%R http://dx.doi.org/10.2147/OAJSM.S37065
%X cise training improves fasting glucose control Original Research (1337) Total Article Views Authors: Norton L, Norton K, Lewis N Published Date November 2012 Volume 2012:3 Pages 209 - 214 DOI: http://dx.doi.org/10.2147/OAJSM.S37065 Received: 22 August 2012 Accepted: 09 October 2012 Published: 16 November 2012 Lynda Norton,1 Kevin Norton,2 Nicole Lewis2 1School of Medicine, Flinders University, Adelaide, Australia; 2School of Health Science, University of South Australia, Adelaide, Australia Purpose: Numerous studies have measured changes in fasting blood glucose (FBG) levels in response to physical activity (PA) interventions. While studies involving clinical populations such as type 2 diabetics typically report significant reductions, most others report no change in FBG. This study investigated changes in FBG in apparently healthy adults following a PA intervention. Methods: We measured fingertip samples for FBG pre and post a 40-day PA program in 575 insufficiently active adults. The PA goal was at least 30 minutes of moderate exercise daily, and there was 73% compliance. Results: A PA questionnaire showed the average level of activity was 69 ¡À 46 min/wk preintervention, and this increased to 635 ¡À 458 min/wk postintervention. When the change in FBG was regressed against baseline FBG levels, there was a significant negative relationship (y = 2.623 ¨C 0.471 ¡Á x; r = 0.472; P < 0.0001). The regression line showed, on average, subjects with low pre-study glucose levels had increased FBG while those with high levels had reductions in FBG. Conclusion: It appears that the body's response to PA training is to upregulate glucose control, which is reflected in tighter FBG levels around a physiological set point (5.6 mmol/L, in the present study). Regulation of blood glucose is a complex neuroendocrine process with numerous organs involved, but it was not possible in the present study to determine which of these regulatory steps are involved in exercise-induced changes of FBG.
%K physical activity
%K glucagon
%K insulin sensitivity
%U https://www.dovepress.com/exercise-training-improves-fasting-glucose-control-peer-reviewed-article-OAJSM