%0 Journal Article
%T Comparison of ultra-widefield fluorescein angiography with the Heidelberg Spectralis  noncontact ultra-widefield module versus the Optos  Optomap
%A Witmer MT
%A Parlitsis G
%A Patel S
%A Kiss S
%J Clinical Ophthalmology
%D 2013
%I 
%R http://dx.doi.org/10.2147/OPTH.S41731
%X mparison of ultra-widefield fluorescein angiography with the Heidelberg Spectralis  noncontact ultra-widefield module versus the Optos  Optomap  Original Research (1082) Total Article Views Authors: Witmer MT, Parlitsis G, Patel S, Kiss S Published Date February 2013 Volume 2013:7 Pages 389 - 394 DOI: http://dx.doi.org/10.2147/OPTH.S41731 Received: 17 December 2012 Accepted: 15 January 2013 Published: 21 February 2013 Matthew T Witmer, George Parlitsis, Sarju Patel, Szil¨˘rd Kiss Department of Ophthalmology, Weill Cornell Medical College, New York, NY, USA Purpose: To compare ultra-widefield fluorescein angiography imaging using the Optos  Optomap  and the Heidelberg Spectralis  noncontact ultra-widefield module. Methods: Five patients (ten eyes) underwent ultra-widefield fluorescein angiography using the Optos  panoramic P200Tx imaging system and the noncontact ultra-widefield module in the Heidelberg Spectralis  HRA+OCT system. The images were obtained as a single, nonsteered shot centered on the macula. The area of imaged retina was outlined and quantified using Adobe  Photoshop  C5 software. The total area and area within each of four visualized quadrants was calculated and compared between the two imaging modalities. Three masked reviewers also evaluated each quadrant per eye (40 total quadrants) to determine which modality imaged the retinal vasculature most peripherally. Results: Optos  imaging captured a total retinal area averaging 151,362 pixels, ranging from 116,998 to 205,833 pixels, while the area captured using the Heidelberg Spectralis  was 101,786 pixels, ranging from 73,424 to 116,319 (P = 0.0002). The average area per individual quadrant imaged by Optos  versus the Heidelberg Spectralis  superiorly was 32,373 vs 32,789 pixels, respectively (P = 0.91), inferiorly was 24,665 vs 26,117 pixels, respectively (P = 0.71), temporally was 47,948 vs 20,645 pixels, respectively (P = 0.0001), and nasally was 46,374 vs 22,234 pixels, respectively (P = 0.0001). The Heidelberg Spectralis  was able to image the superior and inferior retinal vasculature to a more distal point than was the Optos , in nine of ten eyes (18 of 20 quadrants). The Optos  was able to image the nasal and temporal retinal vasculature to a more distal point than was the Heidelberg Spectralis , in ten of ten eyes (20 of 20 quadrants). Conclusion: The ultra-widefield fluorescein angiography obtained with the Optos  and Heidelberg Spectralis  ultra-widefield imaging systems are both excellent modalities that provide views of the peripheral retina. On a single nonsteered image, the Optos  Optomap  covered a significantly larger total retinal surface area, with greater image variability, than did the Heidelberg Spectralis  ultra-widefield module. The Optos  captured an appreciably wider view of the retina temporally and nasally, albeit with peripheral distortion, while the ultra-widefield Heidelberg Spectralis  module was able to image the superior and inferior retinal vasculat
%K peripheral
%K retina
%K wide-angle
%K widefield
%K ultra-widefield
%U https://www.dovepress.com/comparison-of-ultra-widefield-fluorescein-angiography-with-the-heidelb-peer-reviewed-article-OPTH