%0 Journal Article %T Relationship between electrodiagnostic severity and neuropathic pain assessed by the LANSS pain scale in carpal tunnel syndrome %A G¨¹rsoy AE %A Koluk sa M %A Babacan Y ld z G %A Kocaman G %A elebi A %A Ko er A %J Neuropsychiatric Disease and Treatment %D 2013 %I Dove Medical Press %R http://dx.doi.org/10.2147/NDT.S38513 %X tionship between electrodiagnostic severity and neuropathic pain assessed by the LANSS pain scale in carpal tunnel syndrome Original Research (574) Total Article Views Authors: G¨¹rsoy AE, Koluk sa M, Babacan Y ld z G, Kocaman G, elebi A, Ko er A Published Date January 2013 Volume 2013:9 Pages 65 - 71 DOI: http://dx.doi.org/10.2147/NDT.S38513 Received: 25 September 2012 Accepted: 20 November 2012 Published: 07 January 2013 Azize Esra G¨¹rsoy, Mehmet Kolukisa, G¨¹lsen Babacan Yildiz, G¨¹lsen Kocaman, Arif elebi, Abd¨¹lkadir Ko er Department of Neurology, Bezmialem Vakif University, Istanbul, Turkey Objective: The aim of the study was to investigate the relationship between the presence of neuropathic pain assessed by the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) scale and electrophysiological findings in patients with carpal tunnel syndrome (CTS). Methods: We studied 124 hands with idiopathic CTS with pain complaints involving hand and wrist. All hands were assessed by the LANSS with which a score of 12 or more is defined as pain dominated by neuropathic mechanisms. These hands were assigned to minimal, mild, moderate, severe, or extreme severe groups according to the results of the median nerve conduction studies. Results: A LANSS score ¡İ 12, suggestive of pain dominated by neuropathic mechanisms, was defined in 59 (47.6%) CTS hands. Pain intensity was significantly higher in CTS hands with a LANSS score ¡İ 12 (P < 0.001). Among electrophysiological findings, compound muscle action potential amplitude was significantly lower in hands with a LANSS score ¡İ 12 compared with hands with a LANSS score < 12 (P = 0.020). Severity of CTS was not significantly different between LANSS ¡İ 12 and LANSS < 12 groups. Electrophysiological severity was significantly higher in CTS hands with evoked pain (P = 0.005) and allodynia (P < 0.001) in LANSS subscore analysis. Conclusion: We suggest that the presence of pain dominated by neuropathic mechanisms in CTS is not related to electrophysiological CTS severity. Neuropathic pain should be assessed carefully in patients with CTS, and an appropriate treatment plan should be chosen, taking into account the clinical and electrophysiological findings together with the true pain classification. %K electrodiagnostic evaluation %K carpal tunnel syndrome %K LANSS %K neuropathic pain %U https://www.dovepress.com/relationship-between-electrodiagnostic-severity-and-neuropathic-pain-a-peer-reviewed-article-NDT