%0 Journal Article
%T Synthesis of Some New Functionalized Bis-thiazolidin-5-one and Bis-thiazolidin-4-one Derivatives
%J American Journal of Chemistry
%@ 2165-8781
%D 2012
%I 
%R 10.5923/j.chemistry.20120205.06
%X A series of bis-thiazolidin-5-one and bis-thiazolidin-4-one derivatives 3and5 was prepared by the treatment of highly functional thiocarbamoyl intermediates 2 and 4 with chloroacetyl chloride and chloroacetic acid, respectively. Treatment of the bis-thiocarbamoyl derivative 4a with diazotized sulphanilic acid affected acetyl cleavage to afford the corresponding arylhydrazono-thiocarbamoyl derivative 6.The title compounds bis-thiazolidin-5-one and bis-thiazolidin-4-one derivatives showed high reactivity towards azo coupling reaction with diazotized sulphanilic acid and Knoevenagel reaction with 4-isopropylbenzaldehyde.
%K Thiocarbamoyl
%K chloroacetyl chloride
%K bis-thiazolidin-5(and 4-)-ones
%K Japp-Klingmann reaction
%U http://article.sapub.org/10.5923.j.chemistry.20120205.06.html