%0 Journal Article %T A Review of the History and Role of UHMWPE as A Component in Total Joint Replacements %J International Journal of Biological Engineering %@ 2163-1883 %D 2011 %I %R 10.5923/j.ijbe.20110101.02 %X Since its introduction as a bearing component for Total Joint Replacements (TJR) by Dr. Charnley in the early 1960¡¯s, Ultra-high molecular weight polyethylene (UHMWPE) has become the gold standard to fabricate one of the articulating surfaces of total hip, total knee and total shoulder prostheses. More than a million TJR¡¯s are performed every year and is a multi-billion dollar industry. In-spite-of the overwhelming success of this medical procedure, aseptic loosening as a result of wear limits its longevity to 15-20 years. This review article deals with the history of UHMWPE, its material properties that make it an ideal candidate for total joints, implant-component fabrication procedures and provides insights as to why some of the implants eventually fail. Alternate bearing components like Co-Cr and Ti alloys and ceramics are beyond the scope of this review. %K TJR %K UHMWPE %K Wear-Debris %K Osteolysis %U http://article.sapub.org/10.5923.j.ijbe.20110101.02.html