%0 Journal Article
%T Synthesis and Characterization of New 1,3-Oxazol-5-(4H)-one Derivatives
%J American Journal of Organic Chemistry
%@ 2163-1301
%D 2012
%I 
%R 10.5923/j.ajoc.20120206.04
%X New 1,3-oxazol-5(4H)-one (3a ¨C b) was synthesized by cyclization of[(Pyridyl-3-yl-carbonyl)amino]acetic acid (2). The starting were readily obtained by acylation of 2-amino acetic acid (Glycine) with nicotinoyl chloride. Imidazole was synthesized by reaction of compounds (3a - b) with hydrazine hydrate (99%). Compounds (4a - b) were converted into a variety of derivatives. All new compounds were characterized by 1H NMR and FTIR spectroscopy.
%K Nicotinic Acid
%K 1
%K 3-Oxazole
%K Triazole
%K Thiadiazole
%K Thiourease
%U http://article.sapub.org/10.5923.j.ajoc.20120206.04.html