%0 Journal Article
%T Development and Validation of the Quantitative Analysis of Cefuroxime Sodium in Powder for Injection by Infrared Spectroscopy
%J Advances in Analytical Chemistry
%@ 2163-2847
%D 2012
%I 
%R 10.5923/j.aac.20120206.02
%X A simple, useful and reproducible infra red spectrophotometric method for quantitative determination of cefuroxime (CFU) in powder for injection was developed. This method involved the measurement of absorbance measurements of the band corresponding to aromatic ring centered by 1475-1600 cm-1. The validation of analytical method was carried out to the study of the following analytical parameters: linearity, specificity, precision, accuracy and robustness. The linearity range was found to be 5.0 to 20.0 ¦Ìg.ml-1(regression equation: y = 0.5053x + 0.0114, r2 = 0.9991). The data show a good precision of the method, since the R.S.D. values are close to 2% and below 5%.The proposed method was successfully applied to the assay of cefuroxime in powder for injection.
%K Infrared Spectroscopy
%K Quantitative Determination
%K Quality Control
%U http://article.sapub.org/10.5923.j.aac.20120206.02.html