%0 Journal Article %T A Simple and Convenient Synthesis of Isolated-Fused Heterocycles Based on: 2-Imino-<i>N</i>-phenyl-2<i>H</i>-chromene-3-carboxamide %A Islam H. El Azab %A Fawi M. Abd El Latif Abd El Latif %J Open Journal of Synthesis Theory and Applications %P 44-57 %@ 2168-1252 %D 2012 %I Scientific Research Publishing %R 10.4236/ojsta.2012.13008 %X Starting from 2-imino-N-phenyl-2H-chromene-3-carbox-amide, (1) a series of functionalized chromenes were achieved; such as, 2-ethoxy-2,3-dihydro-3-phenylchromeno[2,3-d]pyrimidin-4-one (2), and 2-hydrazinyl-2,3-dihydro-3-phenylchromeno-[2,3-d]pyrimidin-4-one (3). Furthermore, reactions of (3) with some of laboratory available compounds gave pyrazoles (4-9, 12, 13a, 13b), tetrazoles (11), 2-(2-benzylidenehydrazinyl)-3-phenyl-3H-chromeno[2,3-d]pyrimidin4(10H)-oneisoxazoles (14), 5-chloro-1-(4-oxo-3-phenyl-4,10-dihydro-3H-chromeno[2,3-d]pyrimidin-2-yl)-3-phenyl-2, 3-dihydro-1H-pyrazole-4-carbonitrile (17), pyrimidines (28a, b), pyridines (29a-29e, 30, 33a, 33b), benzo[b][1, 4]oxazepin-2- amines (32a, b), 3-chloro-4-(2-imino-2H-chromen-3-yl)-1-phenyl-4-(phenylamino) azetidin-2-one (34a-34e) and 2-(2- imino-2H-chromen-3-yl)-3-phenyl-2-(phenyl amino)thiazolidin-4-onee (35a-35e). The structures of these compounds were established by elemental analysis, IR, MS and NMR spectral analysis.

%K 2-Imino-2< %K i> %K H< %K /i> %K -chromen-3-yl %K Chromeno[2 %K 3-< %K i> %K d< %K /i> %K ]pyrimidin-4-one %K ¦Ā-Lactam %K Thiazolidin-4-ones %U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=23870