%0 Journal Article
%T Application Studies of Animal Models in Evaluating Safety and Efficacy of HIV-1 Microbicides<br>动物模型在HIV-1杀微生物剂有效性和安全性评价中的应用
%A ZHU Lin
%A ZHANG Gao-Hong
%A ZHENG Yong-Tang
%A <br>朱林
%A 张高红
%A 郑永唐
%J 动物学研究
%D 2010
%I Chinese Academy of Sciences
%X As the HIV/AIDS pandemic continues unabated,novel prophylactic strategy for the spread of HIV are urgently needed.Topical microbicides are designed to prevent transmission of HIV when applied vaginally or rectally.Although there are many microbicide candidates in the pipeline,animal models for evaluating their safety and efficacy are urgently needed.On the basis of comparing the non-primate small animal models and the non-human primate animal models in evaluating safety and efficacy of HIV microbicides,this...
%K HIV-1
%K Sexual transmission
%K Microbicide
%K Safety and efficacy
%K Animal model<br>HIV-1
%K 性传播
%K 杀微生物剂
%K 有效性及安全性
%K 动物模型
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=7C502F1A6798ACE1B8C57E291C48C7F1&aid=0AADB866459714B1B63F4989C0428FFC&yid=140ECF96957D60B2&vid=4AD960B5AD2D111A&iid=CA4FD0336C81A37A&sid=5C3443B19473A746&eid=228A710F49B6CE58&journal_id=0254-5853&journal_name=动物学研究&referenced_num=0&reference_num=90