%0 Journal Article
%T Genome-Wide Analysis of Epigenetic Modifications
%A Shoudan Liang
%A <br>梁守丹
%J 计算机科学技术学报
%D 2010
%I 
%X In plants and animals, gene expression can be altered by changes that do not alter the sequence of nucleotides in DNA but rather modify the chemical structure of either the DNA or the histones that interact with the DNA. These so-called epigenetic modifications are not transient, but persist through cell divisions. Rapidly advancing technologies, such as next-generation DNA sequencing, have dramatically increased our ability to survey epigenetic markers throughout an entire genome. These techniques are reve...
%K epigenetics
%K non-coding DNA
%K DNA methylations
%K histone modifications<br>基因组分析
%K 遗传修饰
%K 表观
%K DNA测序
%K 组蛋白修饰
%K DNA甲基化
%K 遗传标记
%K 计算方法
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=5B3AB970F71A803DEACDC0559115BFCF0A068CD97DD29835&cid=8240383F08CE46C8B05036380D75B607&jid=F57FEF5FAEE544283F43708D560ABF1B&aid=9E23289AEF15F3B1FBC144E0C13F8645&yid=140ECF96957D60B2&vid=C5154311167311FE&iid=CA4FD0336C81A37A&sid=6209D9E8050195F5&eid=2001E0D53B7B80EC&journal_id=1000-9000&journal_name=计算机科学技术学报&referenced_num=0&reference_num=46