%0 Journal Article
%T Computational Challenges in Deciphering Genomic Structures of Bacteria
%A Ying Xu
%A <br>徐鹰
%J 计算机科学技术学报
%D 2010
%I 
%X This article addresses how the functionalities of the cellular machinery of a bacterium might have constrained the genomic arrangement of its genes during evolution and how we can study such problems using computational approaches, taking full advantage of the rapidly increasing pool of the sequenced bacterial genomes, potentially leading to a much improved understanding of why a bacterial genome is organized in the way it is. This article discusses a number of challenging computational problems in elucidat...
%K bioinformatics
%K microbial genomics
%K genome structure
%K comparative genome analysis
%K biological pathways<br>基因组结构
%K 细菌细胞
%K 计算方法
%K 解密
%K 组织方式
%K 基因组测序
%K 进化过程
%K 结构计算
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=5B3AB970F71A803DEACDC0559115BFCF0A068CD97DD29835&cid=8240383F08CE46C8B05036380D75B607&jid=F57FEF5FAEE544283F43708D560ABF1B&aid=5C96367665F7C7DD37241ED0EB701BA8&yid=140ECF96957D60B2&vid=C5154311167311FE&iid=CA4FD0336C81A37A&sid=8E6AB9C3EBAAE921&eid=09ABD5535D9B6D45&journal_id=1000-9000&journal_name=计算机科学技术学报&referenced_num=0&reference_num=160