%0 Journal Article
%T Issues in the Reconstruction of Gene Order Evolution
%A David Sankoff
%A Chunfang Zheng
%A Adriana Muoz
%A Zhenyu Yang
%A Zaky Adam
%A Robert Warren
%A Vicky Choi
%A Qian Zhu
%A <br>David Sankoff
%A 郑春芳
%A Adriana Muoz
%A 杨振宇
%A Zaky Adam
%A Robert Warren
%A 蔡维仁
%A 祝谦
%J 计算机科学技术学报
%D 2010
%I 
%X As genomes evolve over hundreds of millions years, the chromosomes become rearranged, with segments of some chromosomes inverted, while other chromosomes reciprocally exchange chunks from their ends. These rearrangements lead to the scrambling of the elements of one genome with respect to another descended from a common ancestor. Multidisciplinary work undertakes to mathematically model these processes and to develop statistical analyses and mathematical algorithms to understand the scrambling in the chromo...
%K chromosome rearrangement
%K comparative genomics
%K gene clusters
%K phylogenomics<br>基因组进化
%K 基因顺序
%K 染色体
%K 数学模型
%K 学科工作
%K 相关基因
%K 数学算法
%K 统计分析
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=5B3AB970F71A803DEACDC0559115BFCF0A068CD97DD29835&cid=8240383F08CE46C8B05036380D75B607&jid=F57FEF5FAEE544283F43708D560ABF1B&aid=0BC7CB9CD05CEA90750F1BCA57188538&yid=140ECF96957D60B2&vid=C5154311167311FE&iid=CA4FD0336C81A37A&sid=F3090AE9B60B7ED1&eid=C5154311167311FE&journal_id=1000-9000&journal_name=计算机科学技术学报&referenced_num=0&reference_num=73