%0 Journal Article %T Can We Determine a Protein Structure Quickly? %A Ming Li %A
李明 %J 计算机科学技术学报 %D 2010 %I %X Can we determine a high resolution protein structure quickly, say, in a week? I will show this is possible by the current technologies together with new computational tools discussed in this article. We have three potential paths to explore: X-ray crystallography. While this method has produced the most protein structures in the PDB (Protein Data Bank), the nasty trial-and-error crystallization step remains to be an inhibitive obstacle. NMR (Nuclear Magnetic Resonance) spectroscopy. While the NMR experiment... %K 蛋白质结构预测 %K 计算机科学家 %K X射线晶体学 %K 核磁共振 %K 高分辨率 %K 计算工具 %K 实验比较 %K 数据银行 %U http://www.alljournals.cn/get_abstract_url.aspx?pcid=5B3AB970F71A803DEACDC0559115BFCF0A068CD97DD29835&cid=8240383F08CE46C8B05036380D75B607&jid=F57FEF5FAEE544283F43708D560ABF1B&aid=67CF4DFFFDFD6DD019004AFB08D85DFB&yid=140ECF96957D60B2&vid=C5154311167311FE&iid=CA4FD0336C81A37A&sid=C36EC077A8A90308&eid=F24949CFDB502409&journal_id=1000-9000&journal_name=计算机科学技术学报&referenced_num=0&reference_num=68