%0 Journal Article
%T Protein Interactome Analysis for Countering Pathogen Drug Resistance
%A Limsoon Wong
%A Guimei Liu
%A <br>Limsoon Wong
%A Guimei Liu
%J 计算机科学技术学报
%D 2010
%I 
%X Drug-resistant varieties of pathogens are now a recognized global threat. Insights into the routes for drug resistance in these pathogens are critical for developing more effective antibacterial drugs. A systems-level analysis of the genes, proteins, and interactions involved is an important step to gaining such insights. This paper discusses some of the computational challenges that must be surmounted to enable such an analysis; viz., unreliability of bacterial interactome maps, paucity of bacterial intera...
%K protein complexes
%K protein interactomes
%K drug resistance
%K infectious diseases<br>蛋白质相互作用
%K 耐药性
%K 致病菌
%K 组分
%K 抗菌药物
%K 蛋白质分析
%K 抗病品种
%K 病原体
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=5B3AB970F71A803DEACDC0559115BFCF0A068CD97DD29835&cid=8240383F08CE46C8B05036380D75B607&jid=F57FEF5FAEE544283F43708D560ABF1B&aid=4018B317479FF951ABEFC955F2F54343&yid=140ECF96957D60B2&vid=C5154311167311FE&iid=CA4FD0336C81A37A&sid=2F56B21F91C9B05B&eid=B47A0E731AF43EB2&journal_id=1000-9000&journal_name=计算机科学技术学报&referenced_num=0&reference_num=55