%0 Journal Article
%T Synthesis of heptakis(2,3,6-tri-O-methoxymethyl)-β-cyclodextrin and its application in gas chromatography<br>七(2,3,6-三-O-甲氧甲基)-β-环糊精的合成及其在气相色谱分离中的应用
%A YIN Mingming
%A ZHU Xiaobo
%A LIU Yongliang
%A ZHONG Jiangchun
%A CHEN Fuliang
%A <br>尹明明
%A 朱小波
%A 刘勇良
%A 钟江春
%A 陈福良
%J 色谱
%D 2011
%I 
%X A new chiral stationary phase for gas chromatography, heptakis(2,3,6-tri-O-methoxymethyl)-β-cyclodextrin, was synthesized by substituting the 2,3,6-OH groups of β-cyclodextrin with methoxymethyl groups, and a coated capillary column for gas chromatography was made by coating this new stationary phase with static method. The chromatographic properties and separation abilities of the prepared stationary phase were studied. The test results showed that it possessed good separation abilities to Grob test mixture, disubstituted benzene isomers (e.g. nitrotoluenes, bromotoluenes, dichlorobenzenes, dimethylbenzenes) and some chiral compounds such as methyl 2-hydroxypropionates, ethyl 2-hydroxypropionates, methyl 2-methylsulfonylpropionates. The comparison of chiral separation results between 2,3,6-tri-O-methoxymethyl-β-cyclodextrin and 2,3,6-tri-O-methyl-β-cyclodextrin showed that the separation abilities of the two stationary phases were different and complementary to each other for some chiral ester enantiomers.
%K 环糊精衍生物
%K 固定相
%K 毛细管气相色谱
%K 位置异构体
%K 手性化合物
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=6E709DC38FA1D09A4B578DD0906875B5B44D4D294832BB8E&cid=6579068328FE643F&jid=4D81E042D77AFEC6881D14759692069C&aid=0040FD896AB704F28013BE79A0085A70&yid=9377ED8094509821&vid=771469D9D58C34FF&iid=CA4FD0336C81A37A&sid=C753EB8AC8F551B9&eid=BB0EA31DB1B01173&journal_id=1000-8713&journal_name=色谱&referenced_num=0&reference_num=9