%0 Journal Article
%T Comparison of prevalence of metabolic syndrome in hospital and community-based Japanese patients with schizophrenia
%A Norio Sugawara
%A Norio Yasui-Furukori
%A Yasushi Sato
%A Ikuko Kishida
%A Hakuei Yamashita
%A Manabu Saito
%A Hanako Furukori
%A Taku Nakagami
%A Mitsunori Hatakeyama
%A Sunao Kaneko
%J Annals of General Psychiatry
%D 2011
%I BioMed Central
%R 10.1186/1744-859x-10-21
%X We recruited inpatients (n = 759) and outpatients (n = 427) with a Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV) diagnosis of schizophrenia or schizoaffective disorder from 7 psychiatric hospitals using a cross-sectional design. MetS prevalence was assessed using three different definitions, including the adapted National Cholesterol Education Program Adult Treatment Panel (ATP III-A).The overall MetS prevalences based on the ATP III-A definition were 15.8% in inpatients and 48.1% in outpatients. In a logistic regression model with age and body mass index as covariates, being a schizophrenic outpatient, compared to being a schizophrenic inpatient, was a significant independent factor (odds ratio = 3.66 for males, 2.48 for females) in the development of MetS under the ATP III-A definition. The difference in MetS prevalence between inpatients and outpatients was observed for all age groups in males and for females over 40 years of age.Outpatients with schizophrenia or schizoaffective disorder in Japan had a high prevalence of MetS compared to inpatients. MetS in schizophrenic outpatients should be carefully monitored to minimize the risks. A change of lifestyle might improve MetS in schizophrenic patients.A high prevalence of metabolic syndrome (MetS) has been reported among schizophrenic patients [1-3]. MetS has been related to an increased risk for cardiovascular diseases [4,5], diabetes [6] and mortality [7] and is defined as a cluster of metabolic disturbances including abdominal obesity, atherogenic dyslipidemia, hypertension and hyperglycemia [8].Commonly used definitions for MetS are the National Cholesterol Education Program Adult Treatment Panel (NCEP ATP III) MetS definition [7] and the adapted NCEP ATP III (ATP III-A) definition, proposed by the American Heart Association (AHA) following the American Diabetes Association's (ADA's) lowering of the threshold for impaired fasting glucose to 100 mg/dl [9]. Because abdominal obes
%U http://www.annals-general-psychiatry.com/content/10/1/21