%0 Journal Article
%T Electro-acupuncture could be an effective pretreatment for cerebral ischemia
%A Feng Zhang
%A Yi Wu
%A Jie Jia
%A Qing-Chuan Guo
%J Iranian Journal of Medical Hypotheses & Ideas
%D 2010
%I Tehran University of Medical Sciences
%X "nElectroacupuncture, the integration of traditional Chinese acupuncture and modern electrotherapy, has been used for clinical treatment of cerebral ischemic disease in both eastern and western countries; however, the mechanism underlying its effects is still unknown. It is well known that excessive glutamate results in neuronal excitotoxicity after ischemic stroke. Previous studies have indicated that electro-acupuncture may downregulate the overactivation of glutamate after ischemia, and a recent study implied that electro-acupuncture prior to ischemia could induce brain ischemic tolerance. Based on the present information, we hypothesize that electro-acupuncture could be an effective pretreatment for cerebral ischemia by regulating the glutamatergic system.
%K Electroacupuncture
%K Glutamatergic system
%K Brain ischemic tolerance
%K Pretreatment
%U http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/15418.pdf&manuscript_id=15418