%0 Journal Article
%T Interstitial Lung Disease in a Patient with Chronic Granulomatous Disease
%A Mozhgan Moghtaderi
%A Sara Kashef
%A Nima Rezaei
%J Iranian Journal of Pediatrics
%D 2012
%I Tehran University of Medical Sciences
%X Background: Chronic granulomatous disease (CGD) is an inherited phagocytes defect, characterized by defects of NADPH-oxidase and inability of bacterial killing, which leads to recurrent life-threatening infections. Respiratory problems, which are the major cause of morbidity in CGD, usually result fromrecurrent severe infections; however, vigorous inflammatory response could also cause respiratory diseases.Case Presentation: Herein, an 11 year-old patient with CGD is presented who suffered from chronic cough and dyspnea for 7 years. Considering the results of chest X-ray, high-resolution computedtomography, and pulmonary function test, the diagnosis of interstitial lung disease was made.Conclusion: Early recognition of manifestations associated with CGD and appropriate treatment could prevent further complications and reduce morbidity and mortality in this group of patients.
%K Chronic Granulomatous Disease
%K Interstitial Lung Disease
%K Immunodeficiency
%U http://ijp.tums.ac.ir/index.php/ijp/article/view/1307/pdf