%0 Journal Article %T Birth Defects Data from Surveillance Hospitals in Hubei Province, China, 200l - 2008 %A Lh Tu %A H Li %A Hp Zhang %A Xd Li %J Iranian Journal of Public Health %D 2012 %I Tehran University of Medical Sciences %X Background: To determine the prevalence and characteristics of birth defects in perinatal infants in Hubei Province during 200l-2008.Methods: The prevalence of birth defects in perinatal infants delivered after 28 weeks or more was analyzed in Hubei surveillance hospitals during 200l-2008.Results: The incidence of birth defects in perinatal infants from 200l to 2008 was 120.0 per 10,000 births, and was increased by about 41% from 81. 1 in 2001 to 138.5 per 10,000 births in 2008. The incidence in the first 4 years (2005-2008) was much higher than the latter four (2001-2004) (¦Ö2=77.64 , P <0.05). The difference in prevalence between urban and rural was of no significance in 2008 (¦Ö2=0.03£¬P >0.05), but that between male and female was significant (¦Ö2=5.24 , P <0.05), as the former prevalence was much higher. The prevalence of birth defects was slightly higher among mothers over 35 years old than those under 35 years old, but with no significance (¦Ö2=1.98, P >0.05). The two leading birth defects were cleft lip and/or palate and polydactyly, followed by congenital heart disease, hydrocephaly, external ear malformation and neural tube defects. The prevalence of congenital heart disease was rising.Conclusions: Eight years birth defects data indicate that the birth defect rate was on the rise and the birth defects prevalence in Hubei province should be valued. %K Birth Defect %K Prevalence %K Perinatal Infants %K Surveillance %K Prevention %U http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/20498.pdf&manuscript_id=20498