%0 Journal Article
%T Regio- and stereoselective carbometallation reactions of N-alkynylamides and sulfonamides
%A Yury Minko
%A Morgane Pasco
%A Helena Chechik
%A Ilan Marek
%J Beilstein Journal of Organic Chemistry
%D 2013
%I 
%R 10.3762/bjoc.9.57
%X The carbocupration reactions of heterosubstituted alkynes allow the regio- and stereoselective formation of vinyl organometallic species. N-Alkynylamides (ynamides) are particularly useful substrates for the highly regioselective carbocupration reaction, as they lead to the stereodefined formation of vinylcopper species geminated to the amide moiety. The latter species are involved in numerous synthetically useful transformations leading to valuable building blocks in organic synthesis. Here we describe in full the results of our studies related to the carbometallation reactions of N-alkynylamides.
%K carbometallation
%K enamides
%K organocopper
%K regiochemistry
%K ynamides
%U http://dx.doi.org/10.3762/bjoc.9.57