%0 Journal Article
%T Towards a biocompatible artificial lung: Covalent functionalization of poly(4-methylpent-1-ene) (TPX) with cRGD pentapeptide
%A Lena M£¿ller
%A Christian Hess
%A Ji£¿¨ª Pale£¿ek
%A Yi Su
%J Beilstein Journal of Organic Chemistry
%D 2013
%I 
%R 10.3762/bjoc.9.33
%X Covalent multistep coating of poly(methylpentene), the membrane material in lung ventilators, by using a copper-free ¡°click¡± approach with a modified cyclic RGD peptide, leads to a highly biocompatible poly(methylpentene) surface. The resulting modified membrane preserves the required excellent gas-flow properties while being densely seeded with lung endothelial cells.
%K click chemistry
%K growth factor
%K nitrenes
%K plasma chemistry
%K poly(4-methylpent-1-ene)
%K surface modification
%U http://dx.doi.org/10.3762/bjoc.9.33