%0 Journal Article %T Cytokeratins In Health And Disease %A Shailja Chatterjee %J Oral & Maxillofacial Pathology Journal %D 2012 %I Kairali Society of Oral & Maxillofacial Pathologists %X Objective: Cytokeratins are epithelium-specific intermediate filaments. Their altered expression is evident in various benign, hyperplastic and neoplastic lesions. This review provides an in-depth description of cytokeratin expression patterns in odontogenesis; normal development, hyperplastic/benign and malignant lesions or conditions.Materials and methods: Cytokeratin expression can be studied by numerous techniques like immunohistochemistry, immunofluorescence and in situ hybridization.Results: The variable expressivity of cytokeratins is a subject of continuous deliberation and ongoing research. This paper gives an in-depth analysis of cytokeratin expression in a variety of epithelial tissues.Conclusion: Cytokeratins are universal indicators of epithelium specificity. An alteration of expression can be well understood by means of a proper understanding of their normal presence. %K Cytokeratin %K benign %K malignant %K odontogenesis %K development. %U http://a4add.com/remoteupload/uploads/2040/share/13252232871294_myfile.pdf