%0 Journal Article
%T Synthetic studies toward to the first totalsynthesis of Floribundane B
%A Jo£¿o V. S. Silva
%A In¨ºs S. Resck
%A Angelo H. L. Machado
%J Orbital : the Electronic Journal of Chemistry
%D 2012
%I Universidade Federal de Mato Grosso do Sul
%X Floribundane B is an iridoid recently isolated by D. I. M. de  Mendon a and coworkers from the leaves and the bark of the trunk of Hymenodictyon floribundum B. L. Rob, a plant used in Angola folk medicine to treat fever. Our retrosynthetic analysis to Floribundane B has the Hydroxylactone 1 as key intermediate, which was obtained in  moderated overall yield from the Baylis-Hillman adduct 2. Synthetic studies are on going to afford the first total synthesis of Floribundane B and to confirm the planar structure proposed by D. I. M. de Mendon a and coworkers.
%K Floribundane B
%K iridoid
%K Baylis-Hillman
%K total synthesis
%U http://www.orbital.ufms.br/index.php/Chemistry/article/view/388