%0 Journal Article
%T Microwave ¨C assisted reduction of racemic intermediates potential immunosuppressant
%A Wender A. Silva
%A Jo£¿o V. Silva
%A Larissa G. Maciela
%A Lennine R. Melo
%J Orbital : the Electronic Journal of Chemistry
%D 2012
%I Universidade Federal de Mato Grosso do Sul
%X Immunosuppressant are drugs that reduce the immune response, as important in the treatment of autoimmune diseases and rejection attenuators in organ transplants, the structural point of view generally have a high complexity. Within this context it is indispensable structural simplifications, new molecules are proposed with potential action on a stage is a necessary, reduction system ¦Á,¦Â-unsaturated specifically, chalcone, to their respective alcohol saturated. Therefore, a new method was developed for microwave assisted subsequently coupling to other fragments to the total synthesis of the novel compounds.
%K racemic reductions
%K microwave
%K immunosuppressant
%U http://www.orbital.ufms.br/index.php/Chemistry/article/view/377