%0 Journal Article
%T A convenient one pot preparation of 4-thiazolidinones from enaminolactones
%A Samia Bouzroura
%A Yamina Bentarzi
%A Rachedine Kaoua
%A Bellara Nedjar-Kolli
%J Organic Communications
%D 2010
%I ACG Publications
%X Enaminones 3 and 4, precursors of 4-thiazolidinones, were prepared by condensing tetronic acid (1a) and 4-hydroxy 6-methyl pyrone (1b) respectively with thiosemicarbazide derivatives 2 in refluxing ethanol. The 4-thiazolidinones 6, 7 derivatives were obtained by reacting compounds 3 or 4 with ethyl 2- bromo propionate 5 in the presence of anhydrous sodium acetate in ethalonic medium. Similarly, 9 products were synthesized by action of benzyl 2-bromo acetate 8 on 3.
%K Pyrones
%K tetronic acid
%K thiosemicarbazides
%K enaminones
%K thiazolidinones..
%U http://www.acgpubs.org/OC/2010/Volume%203/Issue%201/2-OC-0909-101.pdf